OBJECTIVE: To study the prevention and cure of Famotidine dispersion tablets(FDT)on experimental gastric ul- cer and compare it with Famotidine tablets(FT) in the dose- response relationships.

Determination of the dissolution for compound famotidine dispersible tablets;

Preparation of monolithic osmotic pump tablets of famotidine;

Drug release mechanism of famotidine time-controlled release pellets;

Treatment of symptoms in gastric acid-related diseases with compound famotidine chewable tablets:evaluation of clinical efficacy and safety

OBJECTIVE To determine the calcium and magnesium concentrations in human serum by flame atomic absorption method after a single oral dose of compound famotidine chewable tablets and to investigate their physiological disposition and whether influence the pharmacokinetic properties of famotidine.