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1)  dextrophan
氧去甲右美沙芬
1.
The dextrophan concentration in plasma samples were determined by HPLC-FLD.
方法:采用两制剂双周期双交叉前后自身对照试验设计,20名健康男性志愿者分别口服单剂量氢溴酸右美沙芬口腔崩解片和氢溴酸右美沙芬片各60 mg(受试制剂和参比制剂),用高效液相色谱(HPLC)-荧光检测法测定血浆中氧去甲右美沙芬的浓度,采用DAS2。
2.
A sensitive HPLC method was developed to determine dextrophan and guaifenesin simultaneously in the human plasma.
建立了同时测定人血浆中氧去甲右美沙芬及愈创木酚甘油醚浓度的高效液相色谱 紫外检测法 ,并初步研究了以上两种药物在人体内的药动学性质。
2)  dextrorphan
去甲右美沙芬
1.
Simultaneous determination of dextrorphan and guaifenesin in human plasma by HPLC;
血浆中去甲右美沙芬和愈创木酚甘油醚的HPLC测定
2.
A HPLC method with fluorescence detection for determination of dextromethorphan (1) and its active metabolite, dextrorphan (2) in human plasma was presented.
建立了简便、准确、灵敏的反相高效液相色谱 -荧光检测法测定人血浆中右美沙芬和活性代谢物去甲右美沙芬的血药浓度。
3)  dextrorphan
O-去甲右美沙芬
1.
Determination of dextrorphan in human plasma and pharmacokinetic study;
人血浆中O-去甲右美沙芬的测定及药代动力学研究
2.
Four rapid and sensitive methods for quantitative analyses of adefovir, dextrorphan, zolmitriptan and erdosteine in plasma were developed and validated by liquid chromatography-tandem mass spectrometry in this thesis.
本文利用液相色谱-串联质谱技术,建立了4种灵敏、快速的定量方法,分别用于血浆中阿德福韦、O-去甲右美沙芬、佐米曲普坦和厄多司坦的测定。
4)  dextrophan
去甲右美沙芬
1.
Determination of dextromethorphan and dextrophan in human urine of Han,Uigur and Kazak nationalities by RP-HPLC;
反相高效液相色谱法测定尿中右美沙芬及去甲右美沙芬的含量与CYP2D6表型分析
2.
Determination of Dextromethorphan and Dextrophan in Human Urine by HPLC and Study on the Discrimination of Phenotype of Cytochrome CYP2D6;
HPLC法测定人尿中右美沙芬及去甲右美沙芬的含量及CYP2D6表型区分研究
5)  dextromethorphan
右美沙芬
1.
Preparation of dextromethorphan oral sustained-release suspensions by ion exchange resin and the in-vitro release kinetics;
右美沙芬树脂口服缓释混悬液的制备及其释药特性研究
2.
Determination of Dextromethorphan in Human Plasma by LC/MS and Study on Its Pharmacokinetics;
LC/MS联用法测定人血浆中右美沙芬的浓度及其药动学研究
3.
Effect of preoperative administration of Dextromethorphan on cough reflex during tracheal extubation;
术前肌注右美沙芬对全麻术后拔管时呛咳反应的影响
6)  Dextromethorphan
氢溴酸右美沙芬,二甲吗喃 ,美沙芬,右甲吗喃
补充资料:美沙芬林
分子式:
CAS号:

性质:又称噻苯二胺。深黄色液体。沸点183~185℃。折射率1.5902。N,N-二甲基-N′-苯基乙二胺与氯化2-噻吩甲基在氨基钠存在下在干燥甲苯中缩合制得。盐酸盐为抗组胺药,治疗荨麻疹等过敏症,具有轻微的特异气味的白色或淡黄色结晶粉末,熔点186~187℃,易溶于水,能溶于乙醇。毒性:小鼠腹腔LD50117mg/kg。

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