In this dissertation,copper-catalysized azide-alkyne 1,3-dipolar cycloaddition was used for chemical modification of PVacet and for synthesis of novel linear polymers to obtain a series of 1,2,3-triazole rings containing polymers in backbones or side-chains.

Synthesis of novel thioureas and thiosemicarbazides containing 1,2,3-triazole;

Synthesis of N_1-(2-phenyl-1,2,3-triazole-4-formyl)-pyrazole derivatives;

Synthesis and Herbicidal Activity of Novel N-(4,6-Disubstituted pyrimidin-2-yl)-1-[substituted pyridyl(thiazolyl)methyl]-5-methyl-1H-1,2,3-triazole-4-carboxamides;

Synthesis of 1-(2,3,4,6-Tetra-O-pivaloyl-β-D-glucopyranosyl)-4-phenyl-1,2,3-triazole;

Synthesis of azidopyridines and 1-pyridinyl-1,2,3-triazoles;

Therefore, we obtained a series of novel compounds by introduction of 2-phenyl-1,2,3-triazole ring into 1,5-benzothiazepine.

In order to obtain new agents of biological activity,we introduce 1H-1,2,3-triazole derivatives which have the extensive biological activity and some small nitrogen heterocycles such as morpholine,aziridine,imidazole and 5-fluorouracil etc.

1H-1,2,3-triazole derivatives are a class of broad biological activity of compounds,they are widely used in industry, agriculture,medicine and other fields.