Determination of Cu, Pb,Zn,As,Sb and Cdin Artemether by ICP-AES;

Artemether’s Technological Innovation Process and its Inspiration for the Chinese New Drug Self-oriented Innovation;

The dominant influential factors for synthesis of β-ARM such as the amount of dichloromethane,the amount of catalyst,the reaction temperature and the reaction time were optimized through single factor experiment and orthogonal experiment.

Crystallization is the key purification process for the quality control of β-artemether, and the fundamental solubility data of β-artemether are crucial for the β-artemether crystallization process.

Coartem and Fansimef in the Treatment of Falciparum Malaria;