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1)  SELDI-TOF-MS
表面增强激光解吸离子化飞行时间质谱
1.
Serum protein fingerprints were detected by SELDI-TOF-MS with CM10 protein-chip,datasets were analyzed and the serum protein fingerprints.
【目的】应用表面增强激光解吸离子化飞行时间质谱(surface enhanced laser desorption-ionization time-of-flight mass spectrometry,SELDI-TOF-MS)技术寻找染矽尘大鼠血清潜在生物标志物,探索建立染矽尘大鼠血清蛋白指纹分类决策树。
2.
Methods Surface enhanced lazar desorption/ionisation-time of flight-mass spectrometry (SELDI-TOF-MS) with immobilized metal affinity capture arrays-Cu (IMAC-Cu) was used to examine the serum of 49 patients with cervical invasive cancer and 7.
方法通过表面增强激光解吸离子化飞行时间质谱仪(sur-face enhanced lazar desorption/ionisation-time of flight-mass spectrometry,SELDI-TOF-MS),铜离子结合芯片(immobilized metal affinity capture arrays-Cu,IMAC-Cu)以及配套软件,检测49例宫颈浸润癌,71例年龄相配的健康女性血清,筛选出有分类意义的差异蛋白,寻找出合理的运算规则,构建决策树分类模型。
3.
Background and purpose:Surface enhanced laser desorption ionization time of flight mass spectrometry (SELDI-TOF-MS) is useful in helping to identify the molecular changes closely related to renal cell carcinoma.
背景与目的:表面增强激光解吸离子化飞行时间质谱(SELDI-TOF-MS)技术有助于筛选肾细胞癌相关的分子变化。
2)  SELDI-TOF-MS
表面增强激光解吸/离子化飞行时间质谱
1.
Methods Surface enhanced laser desorption/ionization time-of-flight mass spectrometry(SELDI-TOF-MS)Proteinchip technology was used to detect plasma from 33 patients with advanced ovarian cancer(FIGO stage Ⅲ or Ⅳ)and 31 control individuals.
方法采用表面增强激光解吸/离子化飞行时间质谱(SELDI-TOF-MS)技术,对33例晚期(FIGOⅢ、Ⅳ期)卵巢癌及31例对照血浆标本进行检测,结合生物信息学的支持向量机(support vector machines,SVM)方法用晚期卵巢癌和对照组血浆的蛋白质谱建立诊断模型;运用此模型对11例早期(FIGOⅠ、Ⅱ期)卵巢癌进行盲法测试以探讨用于早期卵巢癌诊断的可行性。
3)  Surface enhanced laser desorption/ionization time-of-flight mass spectrometry
表面增强激光解吸/离子化飞行时间质谱
1.
Methods Surface enhanced laser desorption/ionization time-of-flight mass spectrometry(SELDI-TOF-MS) CM10 Proteinchip technology was used to detect eight serum and plasma samples.
方法:采用表面增强激光解吸/离子化飞行时间质谱(SELDI-TOF-MS)技术,并选用CM10蛋白质芯片对8名志愿者的血清和血浆标本分别进行检测,经Proteinchip Software 3。
4)  Surfaced enhanced laser desorption/ionization-time of flight-mass spectroscopy
表面增强激光解吸附离子化时间飞行质谱
5)  surface enhanced laser desorption/ionization-time of flight mass spectrometry
表面增强激光解吸附/离子化飞行时间质谱
6)  surface-enhanced laser desorption-ionization-time of flight-mass spectrometry
表面增强激光解吸-离子化-飞行时间质谱
补充资料:基质辅助激光解吸时间飞行质谱
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CAS号:

性质:从原理上讲,它属于激光解吸质谱(LDMS),它与普通LDMS的不同在于,激光不是直接打在试样上使之解吸,而是把试样悬浮在基质中,激光打在基质上,基质吸收并传递激光能量,使基质中的试样解吸出来,试样解吸并电离后进入时间飞行质谱仪中检测。MALDI-TOFMS由于使用了基质辅助,它对激光能量的限制就比较宽了,对不同的试样,改变基质,可以获得更满意的结果。目前MALDI-TOF MS是用来进行药物、生物分子的测定的较好手段。

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