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1)  SELDI-TOF-MS
表面增强激光解析离子化飞行时间质谱
1.
Methods: The sera of health adult, HBV related chronic hepatitis, liver cirrhosis and hepatocellular carcinoma were respectively detected by surface enhanced laser desorption/ionization time-of- flight mass spectrometry (SELDI-TOF-MS).
方法:本研究采用表面增强激光解析离子化飞行时间质谱(SELDI-TOF-MS)技术,对32例正常对照、85例HBV相关慢性肝炎、30例肝硬化和26例肝癌术前患者的血清进行检测,筛选差异蛋白。
2.
Methods Serum samples from 7 cases of HCC patients and 7 cases of HBV infected carriers were collected respectively, special protein or peptide spectra was determined by SELDI-TOF-MS measurement after treating the sample onto two kinds of prote.
方法:选择肝癌患者和慢性肝病患者各7例,采用WCX2、IMAC3这两种芯片,经表面增强激光解析离子化飞行时间质谱技术(SELDI-TOF-MS)测定蛋白质谱,筛选适合本实验血清的较佳蛋白质芯片。
3.
AIM:To determine the feasibility of combined use of surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) and empirical proteomic ontology knowledge base (EPO-KB) for identification of serum biomarkers for colorectal cancer.
目的:探讨表面增强激光解析离子化飞行时间质谱仪(SELDI-TOF-MS)联合蛋白质组学实验数据库方法研究结直肠癌患者血清标志物的可行性。
2)  Surface-enhanced laser desorption ionization time of flight mass spectrometry
表面增强激光解析离子化飞行时间质谱
1.
Object: To compare the diagnosis value of lung adenocarcinoma by traditional tumor marker CYFRA21-1, CEA, CA125,NSE with serum protein markers selected by surface-enhanced laser desorption ionization time of flight mass spectrometry.
目的:比较表面增强激光解析离子化飞行时间质谱技术(SELDI- -TOF-MS)筛选的肺腺癌血清标志蛋白和传统肿瘤标物CYFRA21-1, CEA,CA125,NSE对肺腺癌诊断价值的差异。
3)  surface-enhanced laser desorption/ionization time-of-flight mass spectrometry(SELDI-TOF-MS)
表面增强激光解析离子化飞行时间质谱(SELDI-TOF-MS)
4)  surface enhanced laser desorption/ionization-time of flight-mass spectrometry
表面增强激光解析离子化飞行时间质谱仪
5)  SELDI-TOF-MS
表面增强激光解析电离飞行时间质谱
1.
coli were analyzed by Surface enhanced laser desorption/ionization time-of-flight mass spectra(SELDI-TOF-MS),and the data was collected by Ciphe.
蛋白提取液提取细菌蛋白,干化学法测蛋白浓度,应用表面增强激光解析电离飞行时间质谱技术(SELDI-TOF-MS)检测E。
2.
【Objective】To develop a novel and reliable method for diagnosis of pancreatic cancer by surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS).
目的采用表面增强激光解析电离飞行时间质谱(SELDI-TOF-MS)技术检测血清蛋白指纹图,通过差异蛋白组学筛选胰腺癌特有的蛋白标记物,为研究胰腺癌的病理过程和实验诊断奠定基础。
3.
Surface-enhanced laser desorption ionization time of flight mass spectrometry(SELDI-TOF-MS)technique is a high-throughput proteomics approach with simple operation,high sensitivity and marked specificity,and becomes a variety of tumor markers screening analysis platform based on the protein chips combined with mass spectrometry.
表面增强激光解析电离飞行时间质谱技术是一种操作简单、敏感性高、特异性强的高通量蛋白组学方法,是基于蛋白质芯片和质谱技术联用的多种肿瘤标志物筛选的分析平台。
6)  surface-enhanced laser desorption and ionization time-of-flight mass spectrometry
表面增强激光解析/电离-飞行时间质谱
补充资料:基质辅助激光解吸时间飞行质谱
分子式:
CAS号:

性质:从原理上讲,它属于激光解吸质谱(LDMS),它与普通LDMS的不同在于,激光不是直接打在试样上使之解吸,而是把试样悬浮在基质中,激光打在基质上,基质吸收并传递激光能量,使基质中的试样解吸出来,试样解吸并电离后进入时间飞行质谱仪中检测。MALDI-TOFMS由于使用了基质辅助,它对激光能量的限制就比较宽了,对不同的试样,改变基质,可以获得更满意的结果。目前MALDI-TOF MS是用来进行药物、生物分子的测定的较好手段。

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