1) chiral oxazolidin-one
手性噁唑烷酮
2) oxazolidinones
噁唑烷酮
1.
Synthesis and Antibacterial Activity of(S)-5-Acetamidomethyl-3-[(3-chloro-4-substituted aminomethyl)phenyl]-2-oxazolidinones;
(S)-5-乙酰胺甲基-3-[(3-氯-4-取代胺甲基)苯基]-2-噁唑烷酮的合成及抗菌活性
2.
Linezolid is a new class of oxazolidinones antibacterial agents that has been first used in clinical,it inhibits bacterial protein synthesis by blocking the formation of initiation complex.
利奈唑胺(linezolid)是第一个应用于临床的新型噁唑烷酮类抗生素,通过抑制蛋白起始复合物的形成抑制细菌蛋白质合成,在体内、外对葡萄球菌、链球菌、肠球菌等耐药G+菌有广谱的抗菌作用,其临床疗效已经得到一系列Ⅲ期临床研究证明。
3.
The oxazolidinones are a new class of totally synthetic antibacterials that inhibit protein synthesis via binding to a distinct region of 23S RNA of the 50S ribosomal subunit in prokaryotes.
噁唑烷酮类抗菌剂是一类新型的全合成抗菌药物，作用于细菌蛋白质合成的早期阶段(主要作用靶点是核糖体50S亚基的23S rRNA)，表现出高度的抗耐药性革兰氏阳性菌活性，其代表药物吗啉噁酮(linezolid)已上市。
3) oxazolidinone
噁唑烷酮
1.
Analysis of (4S)-4-benzyl-3-(2′(E)-butenyl)-2-oxazolidinone by nuclear magnetic resonance;
(4S)-4-苄基-3-(2’(E)-丁烯酰基)-2-噁唑烷酮的核磁分析
2.
Studies on synthesis of NCPS supported oxazolidinone chiral auxiliary;
线型聚苯乙烯支载噁唑烷酮手性助剂的合成研究
3.
Preparation of (S)-(+)-4-Phenyl-2-oxazolidinone;
手性4-苯基-2-噁唑烷酮的合成研究
4) chiral oxazaborolidine
手性噁唑硼烷
1.
The asymmetric reduction of 3-chloropropiophenone catalyzed by chiral oxazaborolidines enantioselectively gave S- or R-3-chloro-1-phenylpropanol (2) in good yield.
以自制的手性噁唑硼烷为催化剂,将起始原料β-氯苯丙酮不对称催化氢化还原成(S)-或(R)-手性醇,这一步的化学收率和光学收率都较高。
2.
The asymmetric reduction of ethyl γ-chloroacetoacetate catalyzed by chiral oxazaborolidines enantioselectively gave ethyl R-3-hydroxy-4-chlorobutyrate in good yield and enantioselectivity.
以自制的手性噁唑硼烷为催化剂,将起始原料γ-氯乙酰乙酸乙酯不对称催化氢化还原成(R)-γ-氯-β-羟基丁酸乙酯,这一步的化学收率和光学收率都较高。
3.
The formed chiral oxazaborolidines in situ have been used in the enantioselective borane reduction of prochiral ketones affording the alcohol products with enantiomeric excesses (ee) up to 96%.
首次以天然D-樟脑的衍生物为原料,合成了两个新型龙脑基氨基醇配体,研究了它们与硼烷原位制备成手性噁唑硼烷后,在不对称催化氢化还原前手性芳酮中的性能,得到的手性仲醇的对映体过量(ee)值最高可达96%,还考察了反应温度、时间、溶剂等因素对苯乙酮的不对称氢化还原的化学产率和光学收率的影响。
5) enantioselective reduction
噻唑烷并手性噁唑硼烷
1.
Quantum chemical study on enantioselective reduction of aromatic ketones catalyzed by chiral thiazolidino [3,4-c] oxazaborolidine;
噻唑烷并手性噁唑硼烷催化芳香酮的不对称还原反应的量子化学研究
6) polyoxazolidone
聚噁唑烷酮
1.
Synthesis and characterization of polyoxazolidone;
新型聚噁唑烷酮的合成与表征
补充资料：三甲噁唑烷双酮
分子式：
分子量：
CAS号：
性质：见三甲双酮。
分子量：
CAS号：
性质：见三甲双酮。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条