Objective To evaluate the clinical effect of Periocline Ointment(2% minocycline hydrochloride ointment) as an auxiliary therapy on chronic periodontitis.

Objective:To compare the effect on Minocyclin Hydrochloride tetracycline ointment and Yahao cream in the treatment of acute periodontitis.

Clinical study of minocycline-HCl periodontal stick in the local treatment of periodontitis;

Objective To evaluate the clinical effect of the minocycline-HCL ointment as the auxiliary treatment of periodontits with local drug delivery to patients with non-insulin dependent diabetes periodontits.

Objective:To observe the change of alkaline phosphatase (ALP) in gingival crevicular fliud(GCF) in chronic adult periodontitis after treated the minocycline-HCL sustained release unguent as local drug delivery in the periodontal pocket as the auxiliary treatment of periodontitis.

Preparation of biodegradable chitosan thermosensitive hydrogel for minocycline hydrochloride and its content;

Pharmacokinetics of minocycline hydrochloride in healthy volunteers;

Efficacy of Minocycline Hydrochloride combined with Alobothylon in the treatment of genitourinary Ureaplasma urealytieum infections;

The target sites in the test group were applied with Periocline (2% minocycline hydrochoride ointment), while the ones in control group were applied with Yakang (local metronidazole).

Periocline (2% minocycline hydrochoride ointment) was applied to the teeth in the test group, while Yakang (local metronidazole) was applied in the control group.