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1)  minocycline/pharmacology
米诺环素/药理学
2)  Minocycline [,minəu'saikli:n]
米诺环素
1.
Application of SRP-HPLC with Gradient Elution for Rapid Determination of Minocycline Residues in Milk;
固相萃取-反相高效液相色谱测定牛奶中米诺环素残留量的研究
2.
Effect of minocycline on the in vitro activation and proliferation of murine T lymphocytes;
米诺环素对小鼠T淋巴细胞体外活化和增殖的影响
3.
Influence of Minocycline on expression of intercellular adhesion molecule-1 in rats after focal cerebral ischemia reperfusion;
米诺环素对大鼠局灶性脑缺血再灌注后ICAM-1表达的影响
3)  minocycline [,minəu'saikli:n]
米诺四环素
1.
Intrathecally administration of minocycline on mechanical allodynia and heat hyperalgesia induced by chronic constriction injury of the sciatic nerve in rats;
鞘内注射米诺四环素对慢性坐骨神经结扎大鼠机械痛敏和热痛敏的影响
4)  Cyclosporine/pharmacology
环孢菌素/药理学
5)  cyclosporine/PD
环孢素/药理学
6)  minocycline-HCL
盐酸米诺环素
1.
Clinical study of minocycline-HCl periodontal stick in the local treatment of periodontitis;
盐酸米诺环素牙周条治疗牙周炎的临床研究
2.
Objective To evaluate the clinical effect of the minocycline-HCL ointment as the auxiliary treatment of periodontits with local drug delivery to patients with non-insulin dependent diabetes periodontits.
目的研究盐酸米诺环素软膏辅助糖尿病牙周炎的非手术治疗的临床疗效。
3.
Objective:To observe the change of alkaline phosphatase (ALP) in gingival crevicular fliud(GCF) in chronic adult periodontitis after treated the minocycline-HCL sustained release unguent as local drug delivery in the periodontal pocket as the auxiliary treatment of periodontitis.
目的:观察成人慢性牙周炎应用盐酸米诺环素缓释软膏治疗前后龈沟液中碱性磷酸酶(alkalinephos phatase ,ALP)水平的变化。
补充资料:米诺环素
分子式:C23H27N3O7·HCl
分子量:493.95
CAS号:13614-98-7

性质:黄色结晶性粉末。溶于水,遇光不稳定,味苦。其盐基[10118-90-8]为亮黄色无定形固体。

制备方法:以6-去甲金霉素为原料,采用偶氮盐衍生物法或酯化法制得米诺环素。

用途:抗菌素。抗菌谱、抗菌机理均与四环素相同,其抗菌作用显著强于金霉素、四环素、土霉素,也比多西霉素、美他环素强。金葡萄对该品不易产生耐药性。对四环素耐药的金葡萄、链球菌、大肠杆菌对该品可能敏感。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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