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1)  TrkB
酪氨酸受体激酶B
1.
Effect of Electroacupuncture of Different Acupoints on the Excitability of Detrusor Muscle and the Expression of BDNF and TrkB in the Spinal Cord of Rats with Urinary Retention due to Spinal Cord Injury
电针不同穴位对脊髓损伤后尿潴留大鼠脊髓中脑源性神经营养因子及其酪氨酸受体激酶B表达的影响
2)  TrkB
酪氨酸激酶受体B
1.
The Expression of BDNF and TrkB in Rat Cerebellum;
脑源性神经营养因子及酪氨酸激酶受体B在大鼠小脑的表达
2.
Background and purpose:TrkB, a neurotrophic tyrosine kinase receptor,serves as a potent and specific suppressor of anoikis of non-malignant epithelial cells, and confers high metastatic capacity to these cells.
背景与目的:失巢凋亡抑制因子酪氨酸激酶受体B(tyrosine kinase receptor, TrkB)能诱导正常上皮细胞的恶性转化并且使该细胞具有高转移能力。
3.
Background and purpose:TrkB,a neurotrophic tyrosine kinase receptor,serves as a potent and specific suppressor of anoikis of non-malignant epithelial cells,and induces high invasion capacity in these cells.
背景与目的:失巢凋亡抑制因子酪氨酸激酶受体B(tyrosine kinase receptor,TrkB)能诱导正常上皮细胞的恶性转化并且使该细胞具有高侵袭能力。
3)  Tyrosine kinase receptor B
酪氨酸蛋白激酶受体B
1.
Expression of tyrosine kinase receptor B in human follicle;
酪氨酸蛋白激酶受体B在人卵泡中的表达及意义
2.
BDNF initiate its biological effects by bounding to tyrosine kinase receptor B (TrkB) on the cell membrane.
目的:关于人卵泡液中存在着由卵丘颗粒细胞分泌的脑源性神经营养因子(BDNF)的报道提示:人卵巢中可能有BDNF赖以发挥其生物学效应的特异性高亲合力受体—酪氨酸蛋白激酶受体B(TrkB)的存在。
4)  TrkB
酪氨酸激酶B受体
1.
Study on the Expression of BDNF and TrkB in Rat Hippocampal Formation CA1;
脑源性神经营养因子及酪氨酸激酶B受体在大鼠海马结构CA_1区的表达研究
5)  Protein-tyrosine kinase receptor B
蛋白酪氨酸激酶受体B
6)  Receptor tyrosine kinase
受体酪氨酸激酶
1.
Expression and its clinical significance of receptor tyrosine kinase EphB1 in gastric carcinoma
受体酪氨酸激酶EphB1在胃癌中的表达及其临床意义
2.
Mer is one member of Axl receptor tyrosine kinase family, and its ligand Gas6 can stimulate activity of Mer receptor tyrosine kinase after binding it, and then activate the downstream signal transduction pathway, Mer participates in cell inflammation, apoptosis, tumorigenesis, thrombosis and hemostasis.
Mer是Axl受体酪氨酸激酶家族中的一员,其受体Gas6和Mer结合后可以激活Mer的酪氨酸激酶活性,并激活下游信号传导途径,在细胞炎症、凋亡、血液肿瘤发生发展以及血栓于止血等方面发挥作用。
3.
FLT3,a member of receptor tyrosine kinase III family,is primarily expressed by hematopoietic cells and plays a significant role in hematopoiesis and leukemogenesis.
FMS-like Tyrosine Kinase 3(FLT3)是一种受体酪氨酸激酶,在造血干细胞、前体B细胞等的增殖、分化以及存活中具有重要作用。
补充资料:酪氨酸蛋白激酶抑制剂
分子式:
CAS号:

性质:一类能抑制蛋白质酪氨酸激酶活性的化合物。酪氨酸蛋白激酶能特异性地将磷酸根转移到蛋白质的酪氨酸残基上使其磷酸化,是许多配体活化的生长因子受体和一些癌基因产物,在肿瘤组织中含量高。酪氨酸蛋白激酶抑制剂可作为ATP与酪氨酸蛋白激酶结合的竞争性抑制剂,也可作为酪氨酸的类似物阻断表皮生长因子受体的肽位点和酪氨酸蛋白激酶的编码,抑制细胞增殖,可望开发为抗肿瘤药物,但对完整细胞没有表现出选择性。

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