POLO样蛋白激酶,polo-like kinase,在线英语词典,英文翻译,专业英语

1) polo-like kinase

POLO样蛋白激酶

2) polo-like kinase 1

polo样激酶1

Short hairpin RNA targeting at Polo-like kinase 1 gene was designed and synthesized, which was transfected into RNAi expression vector with EGFP.

以高表达Polo样激酶1(Polo-likekinase1,PLK1)的宫颈癌细胞系HeLa细胞为模型,观察针对PLK1基因的短发夹状RNA(shorthairpinRNA,shRNA)对其凋亡和增殖的影响。

To investigate the effect of lithium on celluar proliferation and transcription of Polo-like kinase 1(Plk1)in lung cancer cells,A549 cells were treated with lithium chloride(LiCl),a highly selective inhibitor of glycogen synthase kinase 3(GSK3),at different concentrations(0～10 mmol/L)and time points(24 hours and 48 hours).

利用糖原合成酶激酶3的抑制剂氯化锂作用于A549细胞,观察细胞形态与增殖的改变及其对Polo样激酶1(Plk1)转录活性的影响。

3) Polo-like kinase 1

Polo 样激酶-1

Measurement of the mRNA level of Polo-like kinase 1 in bronchoscopic bioptic specimens by realtime quantitative PCR;

目的探讨实时荧光定量-聚合酶链反应(RFQ-PCR)检测肺癌活检组织 Polo 样激酶-1(PLK1)mRNA 水平,及其与肺癌临床病理分期、分型的相关性。

4) Polo like kinase 1

保罗样激酶

5) Polo-like kinase 1

保罗样激酶1

6) Polo-like kinase 1

PLK1

BACKGROUND & OBJECTIVE: Polo-like kinase 1 (PLK1), an important cell cycle regulator, is highly expressed in many types of cancer, and is associated with oncogenesis, treatment effectiveness and prognosis.

背景与目的:Polo样激酶1(polo-likekinase1,PLK1)是一种重要的细胞周期调节分子,在多种肿瘤细胞中高表达且与肿瘤发病、治疗和预后密切相关。

To study knockdown effect of small interfering RNA(siRNA) to PLK1(Polo-like kinase 1) mRNA in colorectal cancer cell line SW480 and its mitosis and growth was changed.

为了研究特异小干扰RNA(siRNA)作用于大肠癌细胞株SW 480中PLK1(Polo-like k inase 1)基因表达的mRNA对该细胞分裂生长的影响,设计了对应于PLK1基因表达mRNA不同位点的10种特异siRNA,经化学合成后,用脂质体转染SW 480细胞,实时定量PCR检测PLK1基因的表达,观察不同的siRNA作用强度,并计数细胞了解相应细胞的生长情况,W estern-b lot观察PLK1表达蛋白的变化和流式细胞计数分析细胞周期改变。

参考词条

Polo-like kinase Polo-like kinase-1 Polo-like kinase-1 Polo-like-kinase-1 Polo-like kinase1 (PLK1) Polo like kinasel (Plk1) kinase kinase MAP kinase kinase kinase MAPK kinase kinase MAP kinase kinase riboflavin kinase；riboflavin kinase glycerol kinase arginine kinase 校频国别因素

补充资料：蛋白激酶G

分子式：
CAS号：

性质：一种依赖于cGMP的蛋白激酶。它是由两条多肽链组成的丝氨酸、苏氨酸蛋白激酶。其特点：(1)需与cGMP结合后才表现酶活性；(2)能催化蛋白质中丝氨酸和苏氨酸羟基的磷酸化，但对磷酸化丝氨酸或苏氨酸周围碱性氨基酸的比例要求较高；(3)酶的激活剂、抑制剂以及活性调节作用与蛋白激酶A不同。

说明：补充资料仅用于学习参考，请勿用于其它任何用途。

首页 \| 翻译 \| 影视 \| 论坛 \| 索引 Polo-like kinase 1

1) polo-like kinase POLO样蛋白激酶 2) polo-like kinase 1 polo样激酶1 1. Short hairpin RNA targeting at Polo-like kinase 1 gene was designed and synthesized, which was transfected into RNAi expression vector with EGFP. 以高表达Polo样激酶1(Polo-likekinase1,PLK1)的宫颈癌细胞系HeLa细胞为模型,观察针对PLK1基因的短发夹状RNA(shorthairpinRNA,shRNA)对其凋亡和增殖的影响。 2. To investigate the effect of lithium on celluar proliferation and transcription of Polo-like kinase 1(Plk1)in lung cancer cells,A549 cells were treated with lithium chloride(LiCl),a highly selective inhibitor of glycogen synthase kinase 3(GSK3),at different concentrations(0～10 mmol/L)and time points(24 hours and 48 hours). 利用糖原合成酶激酶3的抑制剂氯化锂作用于A549细胞,观察细胞形态与增殖的改变及其对Polo样激酶1(Plk1)转录活性的影响。 3) Polo-like kinase 1 Polo 样激酶-1 1. Measurement of the mRNA level of Polo-like kinase 1 in bronchoscopic bioptic specimens by realtime quantitative PCR; 目的探讨实时荧光定量-聚合酶链反应(RFQ-PCR)检测肺癌活检组织 Polo 样激酶-1(PLK1)mRNA 水平,及其与肺癌临床病理分期、分型的相关性。 4) Polo like kinase 1 保罗样激酶 5) Polo-like kinase 1 保罗样激酶1 6) Polo-like kinase 1 PLK1 1. BACKGROUND & OBJECTIVE: Polo-like kinase 1 (PLK1), an important cell cycle regulator, is highly expressed in many types of cancer, and is associated with oncogenesis, treatment effectiveness and prognosis. 背景与目的:Polo样激酶1(polo-likekinase1,PLK1)是一种重要的细胞周期调节分子,在多种肿瘤细胞中高表达且与肿瘤发病、治疗和预后密切相关。 2. To study knockdown effect of small interfering RNA(siRNA) to PLK1(Polo-like kinase 1) mRNA in colorectal cancer cell line SW480 and its mitosis and growth was changed. 为了研究特异小干扰RNA(siRNA)作用于大肠癌细胞株SW 480中PLK1(Polo-like k inase 1)基因表达的mRNA对该细胞分裂生长的影响,设计了对应于PLK1基因表达mRNA不同位点的10种特异siRNA,经化学合成后,用脂质体转染SW 480细胞,实时定量PCR检测PLK1基因的表达,观察不同的siRNA作用强度,并计数细胞了解相应细胞的生长情况,W estern-b lot观察PLK1表达蛋白的变化和流式细胞计数分析细胞周期改变。参考词条 Polo-like kinase Polo-like kinase-1 Polo-like kinase-1 Polo-like-kinase-1 Polo-like kinase1 (PLK1) Polo like kinasel (Plk1) kinase kinase MAP kinase kinase kinase MAPK kinase kinase MAP kinase kinase riboflavin kinase；riboflavin kinase glycerol kinase arginine kinase 校频国别因素补充资料：蛋白激酶G 分子式： CAS号：性质：一种依赖于cGMP的蛋白激酶。它是由两条多肽链组成的丝氨酸、苏氨酸蛋白激酶。其特点：(1)需与cGMP结合后才表现酶活性；(2)能催化蛋白质中丝氨酸和苏氨酸羟基的磷酸化，但对磷酸化丝氨酸或苏氨酸周围碱性氨基酸的比例要求较高；(3)酶的激活剂、抑制剂以及活性调节作用与蛋白激酶A不同。说明：补充资料仅用于学习参考，请勿用于其它任何用途。
©2008 dictall.com