1) 5-HT1A receptor ligands
5-HT1A受体配体
1.
The research of 5-HT1A receptor ligands(5-HT1ARL) is beneficial to treat anxiety,depression,pain,etc.
5-HT1A受体(5-HT1AR)是众多5-HTR亚型中研究最为广泛和深入的一类受体,研究5-HT1A受体配体(5-HT1ARL)对于临床上治疗焦虑、抑郁、疼痛等疾病都具有重要的价值。
2) 5-HT1A receptor
5-HT1A受体
1.
In the present study, extracellular recording was used to examine the neuronal activity of the basolateral nucleus (BL) of the amygdala and the effects of systemic administration of the selective 5-HT1A receptor antagonist WAY-100635 on the neuronal activity in the normal rats and rats with 6-hydroxydopamine (6-OHDA)-produced lesions in the substantia nigra pars compacta (SNc).
本文采用玻璃微电极细胞外记录法,观察正常大鼠和6-羟多巴胺(6-hydroxydopamine,6-OHDA)损毁黑质致密部大鼠杏仁基底外侧核(basolateral nucleus,BL)神经元电活动的变化,以及体循环给予选择性5-HT1A受体拮抗剂WAY-100635对神经元电活动的影响。
2.
The present study aimed to explore the effects of 5-HT1A receptors in the distal cerebral spinal fluid-contacting neurons (CSF-CNs) in rat brain parenchyma in neuropathic pain.
本文旨在探讨大鼠脑实质内远位触液神经元中5-HT1A受体的分布及其在神经病理性痛中的作用。
3.
Objective To explore the effects of citalopram on the expression of 5-HT1A receptor in the dentate gyrus in a rat model of post-stroke depression(PSD),and its pharmacological mechanisms in the treatment of PSD in rats.
day-1)干预4周,荧光实时定量PCR和Western印迹方法检测并比较CMS开始后第19、28天各组大鼠海马齿状回5-HT1A受体的基因(mRNA表达水平)和蛋白表达水平。
3) serotonin 1A receptor
5-HT1A受体
1.
Observation the function of Citalopram on hippocampus neurogenesis and serotonin 1A receptor expression in transient cerebral ischemic rat;
全脑缺血大鼠海马自体神经干细胞动员与5-HT1A受体表达关系的初步研究
4) 5-HT1A–R
5-HT1A-受体(5-HT1A-R)
5) 5-HT_(1A/1B) receptors
5-HT1A/1B受体
1.
5-HT_(1A/1B) receptors,α_2-adrenoceptors and the post-receptor adenylate cyclase activation in the mice brain are involved in the antidepressant-like action of agmatine;
同时伍用β受体/5-HT1A/1B受体阻断剂吲哚洛尔(pindolol,PIN,20 mg。
6) 5-HT1A receptor mRNA
5-HT1A受体mRNA
1.
Objective The purpose of this study was to investigate the changes in expression of 5-HT1A receptor mRNA in rat parafascicular nucleus(Pf)induced by coronary artery occlusion(CAO).
目的观察急性心肌缺血期大鼠丘脑束旁核神经元5-HT1A受体mRNA不同时间点表达的变化,以探讨5-HT1A受体在丘脑束旁核痛觉整合和调制中的作用。
补充资料：N-受体
N-受体
存在于交感神经和副交感神经节、神经元的突触后膜和神经肌肉接头的终板膜上的受体。能与乙酰胆碱结合产生兴奋性突触后电位和终板电位，导致节后神经元和骨骼肌的兴奋。这类受体也能与烟碱相结合，产生相似的效应，故又称为"烟碱型受体"。据N型受体存在部位的不同，又分成两个亚型，存在于神经节神经元突触后膜上的受体为N2受体，存在于骨骼肌终板膜上的受体为Nl受体。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条