Samples consisted of 10 women carrying male trisomy 21 fetuses,30 carrying euploid male fetuses,and 30 carrying female fetuses.

15% (112/130) cases with typical trisomy 21, 8.

Advances in study on relationship between maternal deficiency of folic acid and fetal trisomy 21 syndrome;

The use of the primed in situ labeling technique in the diagnosis of 21-trisomy syndrome;