1) amylase secretion
酶分泌
1.
Using the measurment of amylase activity, influences of U73122, an inhibitor of phospholipase C(PLC), and trifluoperazine, an inhibitor of calmodulin (CaM), on amylase secretion stimulated by carbachol(CCh), cholecystokinin octapeptide (CCk-8) and saikosaponin(I) in rat pancreatic acini were studied.
应用碘淀粉比色法检测淀粉酶活性技术 ,以卡巴可 ( CCh)及八肽胆囊收缩素 ( CCk-8)为阳性对照药 ,研究了磷脂酶 C( PLC)抑制剂 U731 2 2和钙调素 ( Ca M)抑制剂三氟吡啦嗪 ( trifluoperazine)影响柴胡皂甙 ( I) [SA( I) ]刺激大鼠胰腺腺泡酶分泌的剂量依赖性和分泌动力学特征 。
2) β-secretase
β-分泌酶
1.
β-secretase Interracts with Divalent Cation Tolerant Protein CUTA;
β-分泌酶与二价阳离子耐受蛋白CUTA存在相互作用
2.
The effect of TO901317 on the expression of β-secretase and β-amyloid peptide in hippocampal neuron;
TO901317对海马神经元β-分泌酶表达及β-淀粉样肽生成的影响
3.
Cerebral ischemia injury-induced β-amyloid formation in astrocytes associated with increases of β-secretase in rat brain;
大鼠缺血性脑损伤致星形神经胶质细胞内β-淀粉样蛋白聚集与β-分泌酶增加相关
3) γ-secretase
γ分泌酶
1.
Assembly of γ-secretase for production of β-amyloid;
催化淀粉样蛋白产生的γ分泌酶的组装
2.
Integral membrane protein presenilin 1(PS1) represents the catalytic component of γ-secretase, and is the crucial protease in the production of β-amyloid (Aβ).
膜蛋白presenilin1(PS1)是γ分泌酶的催化组分,是催化产生β淀粉样蛋白(β-amyloid,Aβ)的关键蛋白酶,因此也是治疗阿尔茨海默病(Alzheimer’s disease,AD)的主要靶点。
3.
Objective Previous studies have revealed that γ-secretase is involved in the pathogenesis of Alzheimer\'s disease.
处理超表达组(T)和对照组(C)细胞,并收集纯化过程中含γ分泌酶复合物的样本,用Western blotting检测γ分泌酶复合物重要组分Nicastrin(NCT)、Presenilin-1(PS-1)以及TMP21的蛋白表达量。
4) β-secretase
β分泌酶
1.
A screen assay of β-secretase inhibitors in vitro;
β分泌酶抑制剂体外筛选模型的构建与验证
2.
Construction and identification of RNA interfering vector targeting β-secretase;
靶向β分泌酶RNA干扰质粒的构建与鉴定
3.
New development of β-secretase;
酶解淀粉样前体蛋白的β分泌酶研究进展
5) γ-secretase
γ-分泌酶
1.
Applying Gal4/VP16-UAS and Dual-Luciferase reporter gene system to detecting the activity of γ-secretase;
利用Gal4/VP16-UAS和双荧光素酶报告基因系统检测γ-分泌酶活性
2.
Transcriptional Regulation of APH-1A and PEN-2, Two Key Components of γ-secretase Complex;
γ-分泌酶组分基因APH-1A和PEN-2的转录调控
3.
Aβ is derived from β-amyloid precursor protein (APP) through sequential proteolytic cleavages by β-secretase (BACE1) and γ-secretase.
Aβ是由淀粉样前体蛋白(amyloid precursor protein,APP)经β-分泌酶(BACE)和γ-分泌酶水解产生的,因此BACE1在AD的形成过程中发挥重要作用。
补充资料：胰酶分泌素
分子式：
CAS号：
性质：又称缩胆促胰素，肠促胰酶素，胆囊收缩素，胰酶分泌素。猪上部十二指肠黏膜提取而得的单链多肽激素。由33个氨基酸组成。一种消化道激素，刺激胰腺外分泌腺分泌和生长，也在饱感，痛觉及神经传导等方面具有作用。由十二指肠、空肠、回肠的M[I]细胞分泌。用于胰外分泌功能试验。
CAS号：
性质：又称缩胆促胰素，肠促胰酶素，胆囊收缩素，胰酶分泌素。猪上部十二指肠黏膜提取而得的单链多肽激素。由33个氨基酸组成。一种消化道激素，刺激胰腺外分泌腺分泌和生长，也在饱感，痛觉及神经传导等方面具有作用。由十二指肠、空肠、回肠的M[I]细胞分泌。用于胰外分泌功能试验。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条