1) ataxia-telangiectasia-like disease
共济失调-毛细血管扩张样疾病
1.
The MRN complex constitutes of MRE11,NBS1 and RAD50,and the deficiency of MRE11 and NBS1 caused disorder named ataxia-telangiectasia-like disease(ATLD) and Nijmegen breakage syndrome(NBS),respectively.
MRN复合物包括MRE11、NBS1、RAD50,此复合物中的MRE11或NBS1缺失或突变会导致人的共济失调-毛细血管扩张样疾病、Nijmegen断裂综合征。
2) ataxia-telangiectasia
毛细血管扩张性共济失调症
1.
Objective To study the effects of ataxia-telangiectasia mutation ATM on cell cycle after irradiation.
方法采用流式细胞技术,以源于正常人皮肤的纤维细胞系GM0639(GM细胞)和毛细血管扩张性共济失调症(AT)患者皮肤的纤维细胞系AT5BIVA(AT细胞)为对照,检测比较AT细胞、GM细胞、AT-ATM+细胞经60Coγ射线照射0、1、3、5、7、9 Gy后细胞周期的差异。
2.
High radiosensitivity of fibroblast cells (AT5BIVA cells) from skin of Ataxia-telangiectasia (A-T) pa-tients were studied by comparing with GM0639 (GM cells) from the skin of healthy adult.
研究毛细血管扩张性共济失调症(AT)患者皮肤的成纤维细胞系AT5BIVA(AT细胞)的应对电离辐射导致细胞氧化损伤的能力。
3.
The study is to observe effects of exogenous ATM gene on mRNA expression of hTERT (human te- lomerase reverse transcriptase) in fibroblast cells (AT5BIVA cells) from skin of Ataxia-telangiectasia (AT) patients and to study the regulation of ATM to hTERT.
通过观察外源性毛细血管扩张性共济失调症突变基因(Ataxia-telangiectasiamutation,ATM)对毛细血管扩张性共济失调症(Ataxia-telangiectasia,AT)患者皮肤的成纤维细胞系AT5BIVA(AT细胞)端粒酶逆转录酶(humantelomerasereversetranscriptase,hTERT)mRNA表达的影响,探讨ATM对hTERT的调控作用。
3) Ataxia telangiectasia
共济失调性毛细血管扩张
4) Ataxia telangiectasia mutated
毛细血管扩张性共济失调突变基因
5) Ataxia telangiectasis
共济失调毛细血管扩张症
1.
Ataxia telangiectasis is caused by the mutation of AT gene (ATM) and it is characterized by hypersensitivity to the radiation.
共济失调毛细血管扩张症(ataxiatelangiectasis,AT)是由ATM(ataxiatelangiectasismutant)基因突变所致,其突出特点是对放射线敏感。
2.
The mutation of AT gene(ATM) leads to the AT disease(ataxia telangiectasis), the cancer incidence of AT patients and its carriers are significantly higer than the normal persons.
共济失调毛细血管扩张症基因的突变 (ataxiatelangiectasismutatedgene,ATM)导致AT疾病 (共济失调毛细血管扩张症 )。
6) ATM
[英][,eɪ ti: 'em] [美]['e 'ti 'ɛm]
共济失调毛细血管扩张症突变基因
1.
ATM and Telomere Instability;
共济失调毛细血管扩张症突变基因与端粒不稳定性关系研究进展
补充资料：毛细血管扩张
毛细血管扩张
telangiectasis
是由于大量毛细血管前括约肌舒张，使大量真毛细血管网同时开放的现象。在炎症情况下，由于血管活性物质的增多和代谢产物的增加，可引起毛细血管扩张。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条