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1)  5-lipoxygenase
5-脂氧化酶
1.
Expression of 5-lipoxygenase mRNA in the peripheral polymorphonucler leukocytes of patients with systemic lupus erythematosus;
系统性红斑狼疮患者外周血多形核细胞5-脂氧化酶mRNA的表达研究
2.
Objective:To observe the effects of Huzhang Gout Granule (HZGG),a compound traditional Chinese herbal medicine,on cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) activities,the two important oxidases in the course of inflammation,so as to investigate the possible anti-inflammatory mechanism of HZGG.
目的:观察虎杖痛风颗粒对环氧化酶(cyclooxygenase,COX)和5-脂氧化酶(5-lipoxygenase,5-LOX)活性的影响,探讨虎杖痛风颗粒抗炎的可能机制。
3.
Eicosanoids such as LTs are released via 5-lipoxygenase(5-LO).
白三烯(LTs)是促进炎症反应的脂类调控因子,在心血管组织中具有强烈的致炎作用,5-脂氧化酶(5-LO)能够氧化花生四烯酸生成LTs等花生酸类物质。
2)  5-lipoxygenase
5-脂氧酶
1.
Effect of herba schizonepetae volatile oil (STO) on activity of 5-lipoxygenase in rat thoracic cavity leukocytes;
荆芥挥发油对大鼠胸腔白细胞5-脂氧酶活性的影响
2.
Arachidonate 5-lipoxygenase Modulates Traumatic Brain Injury and Neurite Outgrowth;
花生四烯酸5-脂氧酶调节脑外伤和神经突起生长的作用
3.
Expression and Functional Modulations of 5-lipoxygenase after Ischemic Brain Injury;
5-脂氧酶在脑缺血损伤后的脑内表达及其功能调节特点
3)  5-lipoxygenase
5-脂氧合酶
1.
Down-regulation of 5-lipoxygenase Expression in Pancreatic Cancer Cell by Triptolide;
雷公藤内酯醇降调胰腺癌细胞5-脂氧合酶表达作用研究
2.
Triptolide induces apoptosis of pancreatic cancer cells and affects expression of 5-lipoxygenase and apoptotic gene;
雷公藤内酯醇诱导胰腺癌细胞凋亡及对5-脂氧合酶和凋亡基因表达的影响
3.
Expression of 5-lipoxygenase in gastric cancer and its correlation with phosphorylated Akt;
胃癌组织中5-脂氧合酶的表达及其与磷酸化Akt的相关性
4)  5–LOX
5–脂氧合酶
5)  COX/5-LOX dual inhibitors
环氧化酶/5-脂氧化酶双重抑制剂
1.
In addition,COX/5-LOX dual inhibitors appear to be almost free from gastric toxicity,.
现有的非甾体抗炎药大多存在胃肠道不良反应或心脏病发作和心肌梗死等方面的副作用,而环氧化酶/5-脂氧化酶双重抑制剂不仅具有较强的解热、镇痛、抗炎和抗风湿等作用,而且未发现有心脏病发作、心肌梗死和胃肠道损伤的危险,因此环氧化酶/5-脂氧化酶双重抑制剂已成为研究新一代非甾体抗炎药的途径。
6)  lipoxygenase
脂氧化酶
1.
Inhibition of lipoxygenase by the extracts from the medicinal plants of Selaginella genus;
卷柏属7种药用植物的提取物对脂氧化酶的抑制作用
2.
Study on the Inhibition of Xantine Oxidase, Lipoxygenase, and Cyclooxygenase by Seven Kinds of Medicinal Plants from Selaginella;
七种卷柏属药用植物抑制黄嘌呤氧化酶、脂氧化酶和环氧化酶的活性作用研究
补充资料:脂氧化酶
分子式:
CAS号:

性质:一种广泛存在的含铁的酶,可以催化来自植物的不饱和脂肪酸,使氧加成到其双键上,形成氢过氧化物,继而使油脂或含油脂食物发生酸败、变质。它不仅破坏油脂,还破坏可氧化的脂溶性维生素,如维生素E和胡萝卜素等。

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