1)  TK
TK
1.
WTP53 gene combined with TK and CD inhibited the growth of colon carcinoma cell line SW480;
WTP53联合双自杀基因CD和TK抑制结肠癌细胞SW480生长
2.
Analysis of loss of heterozygosity in tk gene of L5178Y mouse lymphoma cells induced by colchicine and vincristine;
秋水仙碱和长春新碱诱导L5178Y小鼠淋巴瘤细胞tk基因杂合性缺失分析
3.
Mutational spectra in the tk gene of mouse lymphoma cells induced by acrylamide;
丙烯酰胺诱导小鼠淋巴瘤细胞tk基因突变谱的实验研究
2)  tk gene
tk基因
1.
Study on Construction of the homologous recombinant adenovirus tk gene;
腺病毒-tk基因同源重组系统构建的研究
2.
Construction and identification of recombinant adenovirus with rPB-DR promoter and TK gene;
含rPB-DR启动子和TK基因的重组腺病毒的构建和鉴定
3.
Relation between immune response and bystander effect when using tk gene to treat therapy glioma;
tk基因治疗脑胶质瘤时的免疫反应与旁观者效应的关系
3)  CD-TK
胞嘧啶脱氨酶-胸苷激酶
4)  CD-TK
CD-TK
1.
Lethal effects of adenovirus-mediated CD-TK gene on human bladder tumor cell;
腺病毒介导的CD-TK融合基因联合GCV和/或5-Fc对人膀胱癌细胞的杀伤作用
2.
Experimental Study on CD-TK Double Suicide Gene Systems and Genistein for Prostate Carcinoma;
CD-TK融合双自杀基因联合GEN治疗前列腺癌的实验研究
5)  HSV-tk
人单纯疱疹病毒胸苷激酶
1.
Objective To observe cytocidal efficacy of γ-rays combined with HSV-tk/GCV gene therapy on murine Lewis lung carcinoma cells in vitro and to explore the mechanism of the combined effects.
目的研究γ射线与人单纯疱疹病毒胸苷激酶(HSV-tk)/丙氧鸟苷(GCV)基因治疗系统联合应用对Lewis肺癌细胞的杀伤作用及其可能机制。
6)  hsv-tk
单纯疱疹病毒胸苷激酶
1.
Aim:To construct a recombinant eukaryotic expression vector containing α-fetoprotein(AFP) promoter-mediated HSV-TK suicide gene,and analyze its specific expression on AFP-positive hepatoma cells.
目的:构建甲胎蛋白(AFP)启动子介导的单纯疱疹病毒胸苷激酶(HSV-TK)重组真核表达载体,并检测其在AFP阳性肝癌细胞株的特异性表达。
2.
To improve the effectiveness of radiotherapy and chemotherapy to these tumours, a eukaryotic expression vector expressing herpes simplex virus-thymidine kinase (HSV-TK) regulated by hypoxia responsive element (HRE) under hypoxia was constructed.
本研究拟构建一种由缺氧反应元件(hypoxia responsive element,HRE)调控的单纯疱疹病毒胸苷激酶(herpes simplex virus-thymidine kinase,HSV-TK)基因的真核表达载体,观察HRE能否增强HSV-TK/丙氧鸟苷(gancyclovir,GCV)系统对乏氧环境中的人Ewing肉瘤细胞系(SK-ES-1细胞)的杀伤作用,为弥补放、化疗的不足探索有效的治疗方法。
参考词条
补充资料:ω-agatoxin TK
分子式:
CAS号:

性质:指由漏斗网蜘蛛(Agelenopsis aptera)中提取的一类活性肽物质,其中以ω-agatoxin TK为例,其分子的一级结构如下:Glu-Asp-Asn-Cys-Ile-Ala-Glu-Asp-Tyr-Gly-Lys-Cys-Thr-Trp-Gly-Gly-Thr-Lys-Cys-Cys-Arg-Gly-Arg-Pro-Cys-Arg-Cys-Ser-Met-Ile-Gly-Thr-Asn-Cys-Glu-Cys-Thr-Pro-Arg-Leu-Ite-Met-Glu-Gly-Leu-D-Ser-Phe-Ala分子式中4-20、12-25、19-36、27-34间存在有二硫键。在20世纪90年代它被发现是一种潜在的P-型钙通道阻断剂。

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