1)  HSV-TK
HSV-TK
1.
ATRA enhances the bystander effect of HSV-TK/GCV on BIU-87 cell line in vitro;
全反式维甲酸增强HSV-TK/GCV对BIU-87细胞旁观者效应的观察
2.
Retrovirus and adenovirus mediated HSV-tk/NAS tumor gene therapy system have been established respectively.
单纯疱疾病毒胸苷激酶基因(HerpesSimplexVirus-ThymidineKinase,HSV-tk),配合核苷酸类似物(NAS)GCV或ACV的基因治疗是目前肿瘤基因治疗领域中一种较有希望的治疗方法。
3.
Part 1 Construction of Bicistronic Lentiviral vectorscarrying HSV-TK and EGFP geneObject To construct CMV-mediated and LEC specific promoter LEP503-mediated Lenti-HSV-tk-EGFP vector, and give a novel lentiviral vector platform for the treatment of posterior capsular opacification (PCO).
第一部分慢病毒载体构建、病毒包装和纯化 目的构建广谱(CMV)和特异性启动子(LEP503)调控的Lenti-HSV-tk载体,建立高效的慢病毒转基因平台。
2)  HSV-TK
单纯疱疹病毒-胸苷激酶
3)  HSV-tk
人单纯疱疹病毒胸苷激酶
1.
Objective To observe cytocidal efficacy of γ-rays combined with HSV-tk/GCV gene therapy on murine Lewis lung carcinoma cells in vitro and to explore the mechanism of the combined effects.
目的研究γ射线与人单纯疱疹病毒胸苷激酶(HSV-tk)/丙氧鸟苷(GCV)基因治疗系统联合应用对Lewis肺癌细胞的杀伤作用及其可能机制。
4)  hsv-tk
单纯疱疹病毒胸苷激酶
1.
Aim:To construct a recombinant eukaryotic expression vector containing α-fetoprotein(AFP) promoter-mediated HSV-TK suicide gene,and analyze its specific expression on AFP-positive hepatoma cells.
目的:构建甲胎蛋白(AFP)启动子介导的单纯疱疹病毒胸苷激酶(HSV-TK)重组真核表达载体,并检测其在AFP阳性肝癌细胞株的特异性表达。
2.
To improve the effectiveness of radiotherapy and chemotherapy to these tumours, a eukaryotic expression vector expressing herpes simplex virus-thymidine kinase (HSV-TK) regulated by hypoxia responsive element (HRE) under hypoxia was constructed.
本研究拟构建一种由缺氧反应元件(hypoxia responsive element,HRE)调控的单纯疱疹病毒胸苷激酶(herpes simplex virus-thymidine kinase,HSV-TK)基因的真核表达载体,观察HRE能否增强HSV-TK/丙氧鸟苷(gancyclovir,GCV)系统对乏氧环境中的人Ewing肉瘤细胞系(SK-ES-1细胞)的杀伤作用,为弥补放、化疗的不足探索有效的治疗方法。
5)  HSV-tk
单纯疱疹病毒胸苷激酶(HSV-tk)
6)  HSV-TK gene
单纯疱疹病毒腺苷激酶
1.
Methods:Retroviral vector containing HSV-TK gene was transfected into PA317 packaging cell, then these PA317 cells were cultivated conventionally.
目的:运用单纯疱疹病毒腺苷激酶/更昔洛韦(HSV-TK/GCV)自杀基因系统治疗模型动物并观察其疗效。
参考词条
补充资料:HSV
分子式:
CAS号:

性质:疱疹病毒中的一种,可以感染人及各种动物。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。