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1)  methyltransferase [,meθil'trænsfəreiz]
甲基转移酶
1.
Whether DNA methyltransferase 3B (DNMT3B) is dere gu lated in hepatocellular carcinoma cell lines is still unclear.
为揭示DNA甲基转移酶3B(DNMT3B)在肝癌中是否参与了肿瘤的发生,应用Westernblotting及细胞免疫化学方法分析DNMT3B蛋白在人的正常肝细胞株、肝癌癌旁细胞株及肝癌癌细胞株中的表达。
2.
This article briefly discusses plant DNA methyltransferase, the mode and the loci of Methylation and the epigenetic phenomenon originated by DNA methylation.
简要论述了植物DNA甲基转移酶、甲基化方式、发生位置及DNA甲基化所引起的表观遗传现象。
3.
The m7G46 modification is produced by a specific m7G46 tRNA methyltransferase.
催化tRNA分子46号位鸟苷酸的7号位N原子甲基化修饰的酶被命名为tRNA(m7G46)甲基转移酶
2)  DNA methyltransferase
甲基转移酶
1.
Molecular cloning and sequence analysis of the Rana tigrina ranavirus(RTV) DNA methyltransferase gene;
虎纹蛙病毒甲基转移酶基因的克隆和分析
2.
Objective To investigate the activity and mRNA expression of DNA methyltransferase(DNMT) in gliomas and the effects of chemotherapy and radiotherapy on them.
目的 了解DNA甲基转移酶在星形细胞瘤中的活性和DNMTmRNA表达水平及放、化疗对它的影响。
3.
Both methylation levels of Jurkat before and after TPL disposal were analyzed by n-MSP; The expression of APC gene, DNA methyltransferase 1 (DNMT1), DNMT3A and DNMT3B were analyzed by RT-PCR; DNA ploid analytical method was used to analyze the effect that TPL would bring on the cell life cycle of the target cell line.
方法采用nMSP和DNA克隆测序检测多种恶性血液病细胞株APC基因的甲基化状态;采用MTT法检测TPL对APC基因高甲基化的人急性淋巴细胞白血病细胞系Jurkat细胞增殖、活力的影响;应用流式细胞仪DNA倍体分析法探讨TPL对Jurkat细胞周期的影响;nMSP法检测药物作用前后APC甲基化状态变化;RT-PCR法检测APC、甲基转移酶DNMT1、DNMT3A、DNMT3B基因mRNA的表达;Westren Blot蛋白免疫印迹法检测APC蛋白的表达。
3)  methytransferase gene
甲基转移酶基因
1.
The object pf this study was utilizing the high effective Agrobacterium-mediated transformation system of soybean embryo tip to introduce three methytransferase genes related to anion scavenging from different salt-toler.
本文的目的是利用农杆菌介导的大豆胚尖高效遗传转化方法,将分别来自三种耐盐性不同的植物的与阴离子清除有关的甲基转移酶基因导入大豆中,以期为植物基因工程探索出一条新途径,同时为大豆的遗传育种提供新资料。
4)  DNA methyltransferases 3A
DNA甲基转移酶3A
1.
Objective To investigate the function of DNA methyltransferases 3A(DNMT3A)in a series of biological process and carcinogenesis and to construct an eukaryotic siRNA targeting on DNMT3A to suppress the expression of DNMT3A gene.
目的:构建DNA甲基转移酶3A(DNA methyltransferases 3A,DNMT3A)siRNA重组质粒稳定表达载体,为进一步探讨DNMT3A在多种生物学过程及肿瘤发生发展中的机制提供工具。
5)  DNA methyltransferase
DNA甲基转移酶
1.
Effects of preimplantation embryos on expressions of DNA methyltransferase 1 in mouse oviduct epithelial cells;
小鼠植入前胚胎对输卵管上皮细胞DNA甲基转移酶1表达的影响(英文)
2.
Effects of mouse preimplantation embryo on expression of DNA methyltransferase-1 mRNA in mouse oviductal epithelium.;
小鼠植入前胚胎对输卵管上皮细胞DNA甲基转移酶-1 mRNA的降调节作用
3.
Expression of mRNA for DNA methyltransferase 1, 3a and 3b in bladder carcinoma;
膀胱癌DNA甲基转移酶1、3a、3b基因的表达
6)  DNA methyltransferase 1
DNA甲基转移酶1
1.
Expression of DNA methyltransferase 1 in human gastric cancer tissue and its significance;
DNA甲基转移酶1在胃癌组织中的表达及意义
2.
Expression of DNA methyltransferase 1 in human cervical carcinoma tissue and cells and its significance;
DNA甲基转移酶1在子宫颈癌组织和细胞中的表达及意义
3.
Expression of DNA methyltransferase 1 in transitional cell carcinoma of bladder
DNA甲基转移酶1蛋白在膀胱移行细胞癌中的表达及其临床意义
补充资料:N-甲基转移酶抑制剂
分子式:
CAS号:

性质: 能够抑制N-甲基转移酶活性的一类化合物。N-甲基转移酶是一种参与由去甲基肾上腺素合成肾上腺素反应的酶。目前已在放线菌MD736-C6发酵液中发现一种能够非特异性抑制兔肺N-甲基转移酶的抑制剂四氢吡啶戊二烯。

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