1) Dnmt2
DNA甲基转移酶2
1.
Molecular Characterization and Expression Pattern of Dnmt2 Gene and DNA Methylation Detection in Crustacean;
甲壳动物DNA甲基转移酶2（Dnmt2）基因的分子特征、表达分析及DNA甲基化水平检测
2) DNA methyltransferases 3A
DNA甲基转移酶3A
1.
Objective To investigate the function of DNA methyltransferases 3A(DNMT3A)in a series of biological process and carcinogenesis and to construct an eukaryotic siRNA targeting on DNMT3A to suppress the expression of DNMT3A gene.
目的:构建DNA甲基转移酶3A(DNA methyltransferases 3A,DNMT3A)siRNA重组质粒稳定表达载体,为进一步探讨DNMT3A在多种生物学过程及肿瘤发生发展中的机制提供工具。
3) DNA methyltransferase
DNA甲基转移酶
1.
Effects of preimplantation embryos on expressions of DNA methyltransferase 1 in mouse oviduct epithelial cells;
小鼠植入前胚胎对输卵管上皮细胞DNA甲基转移酶1表达的影响(英文)
2.
Effects of mouse preimplantation embryo on expression of DNA methyltransferase-1 mRNA in mouse oviductal epithelium.;
小鼠植入前胚胎对输卵管上皮细胞DNA甲基转移酶-1 mRNA的降调节作用
3.
Expression of mRNA for DNA methyltransferase 1, 3a and 3b in bladder carcinoma;
膀胱癌DNA甲基转移酶1、3a、3b基因的表达
4) DNA methyltransferase 1
DNA甲基转移酶1
1.
Expression of DNA methyltransferase 1 in human gastric cancer tissue and its significance;
DNA甲基转移酶1在胃癌组织中的表达及意义
2.
Expression of DNA methyltransferase 1 in human cervical carcinoma tissue and cells and its significance;
DNA甲基转移酶1在子宫颈癌组织和细胞中的表达及意义
3.
Expression of DNA methyltransferase 1 in transitional cell carcinoma of bladder
DNA甲基转移酶1蛋白在膀胱移行细胞癌中的表达及其临床意义
5) DNA methyltransferase
DNA甲基化转移酶
1.
Objective:To study transcription level and catalytic activity of DNA methyltransferase (Dnmts) in lung cancer cell line A549 exposed in 5-Aza-CdR (5-Aza-2’-deoxycitydine),and the role of Dnmts in the process.
目的:研究5-氮杂-2’-脱氧胞苷(5-Aza-2’-deoxycitydine,5-Aza-CdR)处理肺癌细胞株A549后,DNA甲基化转移酶(DNA methyltransferase,Dnmts)转录水平及其活性的变化,以及细胞生长状态的改变。
6) DNA methyltransferases
DNA甲基转移酶
1.
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription,induce gene silencing at the participation of many regulators.
DNA甲基化由DNA甲基转移酶催化,在多种调节因子的参与下,与组蛋白修饰相互作用,抑制基因转录,导致基因沉默。
2.
It may result from down-regulating DNA methyltransferases, DNMT1 and DNMT3B, or up-regulating the histone acetylation that allows chromatin unfolding and the accessibility of regulators for transcriptional activation in the p15 promoter.
应用甲基化特异性聚合酶链反应(MSP)检测PHI作用前后Molt-4细胞株p15基因甲基化状态的变化;半定量逆转录-聚合酶链反应(RT-PCR)检测Molt-4细胞经过PHI处理后DNA甲基转移酶DNMT1、DNMT3A、DNMT3B、p15基因的mRNA的表达变化;用蛋白免疫印迹(Western blotting)检测Molt-4细胞经过PHI处理后的P15蛋白的表达。
3.
Objective To investigate the relationship between the expression of DNA methyltransferases(DNMT)and clinical prognosis in children with acute leukemia(AL).
目的通过检测DNA甲基转移酶(DNMT)基因在AL患儿中的表达水平,探讨其与临床预后之间的相关性。
补充资料：转移
转移
metastasis
恶性肿瘤细胞(有时还指侵入的病原体）通过血管、淋巴管或其他途径，从原发病灶扩散到与其不直接相连的部位或器官，并在扩散区形成了同样的病变，如结核菌的转移，恶性肿瘤的转移。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条