1) DNA methyltransferase
DNA甲基化转移酶
1.
Objective:To study transcription level and catalytic activity of DNA methyltransferase (Dnmts) in lung cancer cell line A549 exposed in 5-Aza-CdR (5-Aza-2’-deoxycitydine),and the role of Dnmts in the process.
目的:研究5-氮杂-2’-脱氧胞苷(5-Aza-2’-deoxycitydine,5-Aza-CdR)处理肺癌细胞株A549后,DNA甲基化转移酶(DNA methyltransferase,Dnmts)转录水平及其活性的变化,以及细胞生长状态的改变。
2) de novo DNA Methyltransferase
DNA从头甲基化转移酶
1.
Objective To investigate the mRNA expression of de novo DNA Methyltransferase(DNMT1/3a/3b) and methyl-CpG Binding Protein2(MeCP2) in spermatozoon by qRealTime-PCR.
目的通过体外分离成熟的精子,利用实时荧光定量PCR(qRealTime-PCR)检测其是否表达DNA从头甲基化转移酶(DNMT1/3a/3b)及甲基CpG结合蛋白(MeCP2),为精子中甲基化表观修饰研究提供依据。
3) DNA methyltransferases 3A
DNA甲基转移酶3A
1.
Objective To investigate the function of DNA methyltransferases 3A(DNMT3A)in a series of biological process and carcinogenesis and to construct an eukaryotic siRNA targeting on DNMT3A to suppress the expression of DNMT3A gene.
目的:构建DNA甲基转移酶3A(DNA methyltransferases 3A,DNMT3A)siRNA重组质粒稳定表达载体,为进一步探讨DNMT3A在多种生物学过程及肿瘤发生发展中的机制提供工具。
4) DNA methyltransferase
DNA甲基转移酶
1.
Effects of preimplantation embryos on expressions of DNA methyltransferase 1 in mouse oviduct epithelial cells;
小鼠植入前胚胎对输卵管上皮细胞DNA甲基转移酶1表达的影响(英文)
2.
Effects of mouse preimplantation embryo on expression of DNA methyltransferase-1 mRNA in mouse oviductal epithelium.;
小鼠植入前胚胎对输卵管上皮细胞DNA甲基转移酶-1 mRNA的降调节作用
3.
Expression of mRNA for DNA methyltransferase 1, 3a and 3b in bladder carcinoma;
膀胱癌DNA甲基转移酶1、3a、3b基因的表达
5) DNA methyltransferase 1
DNA甲基转移酶1
1.
Expression of DNA methyltransferase 1 in human gastric cancer tissue and its significance;
DNA甲基转移酶1在胃癌组织中的表达及意义
2.
Expression of DNA methyltransferase 1 in human cervical carcinoma tissue and cells and its significance;
DNA甲基转移酶1在子宫颈癌组织和细胞中的表达及意义
3.
Expression of DNA methyltransferase 1 in transitional cell carcinoma of bladder
DNA甲基转移酶1蛋白在膀胱移行细胞癌中的表达及其临床意义
6) DNA methyltransferases
DNA甲基转移酶
1.
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription,induce gene silencing at the participation of many regulators.
DNA甲基化由DNA甲基转移酶催化,在多种调节因子的参与下,与组蛋白修饰相互作用,抑制基因转录,导致基因沉默。
2.
It may result from down-regulating DNA methyltransferases, DNMT1 and DNMT3B, or up-regulating the histone acetylation that allows chromatin unfolding and the accessibility of regulators for transcriptional activation in the p15 promoter.
应用甲基化特异性聚合酶链反应(MSP)检测PHI作用前后Molt-4细胞株p15基因甲基化状态的变化;半定量逆转录-聚合酶链反应(RT-PCR)检测Molt-4细胞经过PHI处理后DNA甲基转移酶DNMT1、DNMT3A、DNMT3B、p15基因的mRNA的表达变化;用蛋白免疫印迹(Western blotting)检测Molt-4细胞经过PHI处理后的P15蛋白的表达。
3.
Objective To investigate the relationship between the expression of DNA methyltransferases(DNMT)and clinical prognosis in children with acute leukemia(AL).
目的通过检测DNA甲基转移酶(DNMT)基因在AL患儿中的表达水平,探讨其与临床预后之间的相关性。
补充资料：酒化酶、醇酶、发酵酶
分子式：
CAS号：
性质：又称酒化酶、醇酶、发酵酶。从酵母中分离而得的一系列酶。不耐热。它能催化酒精发酵反应，与糖酵解有关，如磷酸化酶、醛缩酶、葡萄糖磷酸变位酶、葡萄糖6-磷酸酶等。
CAS号：
性质：又称酒化酶、醇酶、发酵酶。从酵母中分离而得的一系列酶。不耐热。它能催化酒精发酵反应，与糖酵解有关，如磷酸化酶、醛缩酶、葡萄糖磷酸变位酶、葡萄糖6-磷酸酶等。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条