Preparation study on iptakalim hydrochloride tablets;

The Influence to the inflammation associated factor and plasma biochemical index on the Spontaneously Hypertensive Rats by Iptakalim Hydrochloride;

Effect of iptakalim hydrochloride on extracellular matrix of kidney in spontaneously hypertensive rats;

Protective Effect of Iptakalim Hydrochloride on Endothelial Cells Injuried with Homocysteine;

Effects of iptakalim hydrochloride on glutamate receptors and spontaneo us synaptic activities in rat hippocampal neurons;

Glybenclamide Attenuates the Cardiovascular Effects of Iptakalim in Rats;

Effects of iptakalim on blood pressure and cardiac function in rats;

Effects of Iptakalim on the expression of KATP protein in cultured human pulmonary artery smooth muscle cells induced by endothelin-1;

Effects of iptakalim on several endocrine hormones associated with glucose metabolism in rats;

Effects of iptakalim on intracellular calcium concentrations, PKA and PKC activities in rat tail artery smooth muscle cells;

Inhibitory effects and mechanisms of iptkalim on the glutamate release from PC12 cells induced by high K~(+1);

AIM: To investigate the effect and mechanism of novel ATP-sensitive potassium channel opener (KCO) iptkalim (IPT) on acute and cocaine challenge-induced alterations in the levels of dopamine (DA) and glutamate (Glu) from nucleus accumbens (NAc), striatum, and prefrontal cortex (PFC) in rats.

Aim: To investigate whether pulmonary vascular remodeling in hypoxic pulmonary hypertensive rats could be prevented by treatment with a selective K ATP CO, iptkalim (Ipt).

Synthesis of prodrugs of tacrine hydrochloride and evaluation of the stability and biodistribution in mice;