1) tumor infiltrating lymphocytes
肿瘤浸润淋巴细胞
1.
Treating hepatocellular carcinoma by injecting tumor infiltrating lymphocytes(TIL) into cancer area through skin.;
局部注射肿瘤浸润淋巴细胞治疗肝癌
2.
TIL(tumor infiltrating lymphocytes) is located around the tumor cells.
肿瘤浸润淋巴细胞(tumor infiltrating lymphocytes,TIL)是指位于肿瘤细胞组织周围的淋巴细胞,具有杀伤肿瘤细胞,降低转移潜能的作用。
3.
The percentage and count of CD4~+ CD25~+ regulatory T cells in tumor infiltrating lymphocytes (TILs) and draining lymph node lymphocytes (DLNLs) derived from 4T1-bearing mice were detected in early and late stage of the tumor by FACS.
结果CD4+CD25+调节性T细胞在肿瘤浸润淋巴细胞中的比例晚期为7。
2) tumor-infiltrating lymphocyte
肿瘤浸润淋巴细胞
1.
Objective: To investigate the optimal efficient ratio of efficacy to target (E/T) and the anti-tumor activity of tumor-infiltrating lymphocytes(TILs) and the mouse s splenocyte lymphocytes stimulated by dendritic cells(DCs) on H22 cells in vitro.
目的:探讨树突状细胞(DC)激活肿瘤浸润淋巴细胞(TIL)和小鼠脾淋巴细胞(小鼠脾LC)的最佳效靶比并观察被有效激活的TIL和小鼠脾LC等对小鼠H22肝癌细胞的体外杀伤作用。
2.
T-lymphocyte subsets and the phenotypes of dendritic cells in tumor-infiltrating lymphocytes (TIL) were detected by flow cytometry (FCM).
方法:用LBP给H22荷瘤小鼠灌胃,连续2周后,测定肿瘤重量,采用流式细胞术检查肿瘤浸润淋巴细胞(tumor-infiltratinglymphocyte,T1L)中T淋巴细胞亚群和DCs的数量,以及协同刺激分子CD80(B7-1)表达的变化。
3.
Objective To determine whether human adenocarcinomas FasL expression is associated with increased apoptotic induction in tumor-infiltrating lymphocyte (TIL) and to provide evidence to support the Fas counterattack theory as a mechanism of immune escape in cancer.
目的 通过对人体肿瘤标本的连续切片 ,测定同一区域肿瘤周边病灶中淋巴细胞上的FasL和肿瘤浸润淋巴细胞凋亡的关系 ,探讨肿瘤免疫逃避的机制。
3) Tumor infiltrating lymphocyte
肿瘤浸润淋巴细胞
1.
Objective: To investigate the activities of tumor infiltrating lymphocytes(TILs) stimulated by dendritic cells(DCs) on mouse breast cancer cells in vitro.
目的:探讨致敏的树突状细胞(DC)激活的肿瘤浸润淋巴细胞(TIL)体外抗小鼠乳腺癌活性。
4) tumor-infiltrating lymphocytes
肿瘤浸润淋巴细胞
1.
To investigate the mechanisms of hepatic cancer cells inducing apoptosis of tumor-infiltrating lymphocytes (TILs) in vitro, hepatic cancer cells were co-cultured with TILs in different effector-taget ratio.
为了探讨肝癌细胞反击肿瘤浸润淋巴细胞(TIL)的机制,在体外进行肝癌细胞和TIL混合培养后,检测两种细胞FasL、Fas、caspase-8基因的表达情况,以及肿瘤细胞反击时TIL凋亡比例的变化。
2.
Objective To study the expression and significance of CD8~+CD28~+ in gastric carcinoma tumor-infiltrating lymphocytes (TIL) to approach the causes which results in TIL function limits.
目的通过研究CD8~+CD28~+在胃癌肿瘤浸润淋巴细胞(TIL)上的表达及其与肿瘤生物学行为的关系和意义,探讨TIL功能受抑制的原因。
5) TIL
[英][til,ti:l] [美][tɪl]
肿瘤浸润淋巴细胞
1.
ObjectiveTo explore the methods to enhance the anti-melanoma activity of TIL.
目的 寻求提高肿瘤浸润淋巴细胞 (TIL)的抗肿瘤活性。
2.
Purpose: The present study probes to access the effect on the proliferation and cytotoxicity of the tumor infiltrating lymphocytes induced by interleukin-12 and activated by dendritic cells loaded with tumor antigen and to evaluate the possibility that IL-12 and DC enhance the specific cytotoxic activity of TILs to tumor cells.
目的：研究白介素12(IL-12)和负载肿瘤抗原的树突状细胞(DC)对肝癌肿瘤浸润淋巴细胞(TIL)的增殖和细胞毒作用的影响，探讨IL-12和DC增强TIL特异性杀伤肿瘤细胞的可能性。
3.
Objective To study the expression and significance of CD8 CD28 in gastric carcinoma infiltrating lymphocytes to approach the causes which results to TIL function limits.
目的:通过研究CD8 CD28在胃癌肿瘤浸润淋巴细胞(tumor-infiltrating lymphocytes, TIL)上的表达及其与肿瘤生物学行为的关系和意义,探讨TIL功能受抑制的原因。
6) Tumor infiltrating lymphocyte
肿瘤浸润性淋巴细胞
1.
Compared with LAK (lymphokine activated killer cells), TIL (tumor infiltrating lymphocyte) has faster proliferation, higher immune activity and stronger killer activity to tumor cells, especially combined with chemotherapy and traditional Chinesemedicine.
肿瘤浸润性淋巴细胞 (tumorinfiltratinglymphocyte,TIL)增殖速度快、免疫活性强 ,比淋巴因子激活的杀伤细胞 (lymphokineactivatedkillercells,LAK)具有更强的特异杀瘤活性 ,与化学治疗及中医中药联用疗效更
补充资料：抗淋巴细胞球蛋白 , 抗淋巴细胞免疫球蛋白,抗人胸腺淋巴细胞球蛋白
药物名称：抗淋巴细胞球蛋白
英文名：Antilymphocyte Globulin
别名：抗淋巴细胞球蛋白 , 抗淋巴细胞免疫球蛋白,抗人胸腺淋巴细胞球蛋白
外文名：Antilymphocyte Globuli ,ALG
适应症：
1.适用于器官移植时的抗免疫排异治疗。用于人的同种异体移植有明显疗效，特别是对肾脏移植的病人。但也有一定局限性，主要是对急性排异期有效，对体液免疫所致的超急性排异无效。与硫唑嘌呤、泼尼松合用可提高脏器移植的成功率。骨髓移植时，供者与受者双方在术前均给以抗淋巴细胞球蛋白，有防止移植物抗宿主反应的作用。 2.自身免疫性疾病。ＡＬＧ对肾小球肾炎、红斑狼疮、类风湿性关节炎、重症肌无力等自身免疫性疾病有良好疗效，对顽固性皮炎、脉管炎、原发性肝炎、交感性眼炎等也有一定疗效
用量用法：
肌注：马ＡＬＧ每次每千克体重４～２０ｍｇ，兔ＡＬＧ每次每千克体重０．５～１ｍｇ，１日１次或隔日１次，１４日为１疗程。 静注：马ＡＬＧ每次每千克体重７～２０ｍｇ，稀释于５０～１００ｍｌ等渗盐水中，于４～６小时内滴完，输入适量等渗盐水，１日１次。
注意事项：
1.肌注可引起局部疼痛、红肿、发热、荨麻疹等，甚至有过敏性休克，静注也可有短时高热（３８～４０℃，持续３小时）、发冷，有时伴有关节痛和气短。静滴可见一过性体温升高与寒颤、低血压、心率增快等。一般在１～２小时内消退。 2.过敏体质者禁用，有急性感染者慎用。 3.采用ＡＬＧ治疗自身免疫性疾病应特别慎重，因长期应用使机体的免疫监管功能降低，给癌变细胞的发展以可乘之机。
规格：冻干粉针剂:25mg(5ml)
类别：免疫抑制剂
英文名：Antilymphocyte Globulin
别名：抗淋巴细胞球蛋白 , 抗淋巴细胞免疫球蛋白,抗人胸腺淋巴细胞球蛋白
外文名：Antilymphocyte Globuli ,ALG
适应症：
1.适用于器官移植时的抗免疫排异治疗。用于人的同种异体移植有明显疗效，特别是对肾脏移植的病人。但也有一定局限性，主要是对急性排异期有效，对体液免疫所致的超急性排异无效。与硫唑嘌呤、泼尼松合用可提高脏器移植的成功率。骨髓移植时，供者与受者双方在术前均给以抗淋巴细胞球蛋白，有防止移植物抗宿主反应的作用。 2.自身免疫性疾病。ＡＬＧ对肾小球肾炎、红斑狼疮、类风湿性关节炎、重症肌无力等自身免疫性疾病有良好疗效，对顽固性皮炎、脉管炎、原发性肝炎、交感性眼炎等也有一定疗效
用量用法：
肌注：马ＡＬＧ每次每千克体重４～２０ｍｇ，兔ＡＬＧ每次每千克体重０．５～１ｍｇ，１日１次或隔日１次，１４日为１疗程。 静注：马ＡＬＧ每次每千克体重７～２０ｍｇ，稀释于５０～１００ｍｌ等渗盐水中，于４～６小时内滴完，输入适量等渗盐水，１日１次。
注意事项：
1.肌注可引起局部疼痛、红肿、发热、荨麻疹等，甚至有过敏性休克，静注也可有短时高热（３８～４０℃，持续３小时）、发冷，有时伴有关节痛和气短。静滴可见一过性体温升高与寒颤、低血压、心率增快等。一般在１～２小时内消退。 2.过敏体质者禁用，有急性感染者慎用。 3.采用ＡＬＧ治疗自身免疫性疾病应特别慎重，因长期应用使机体的免疫监管功能降低，给癌变细胞的发展以可乘之机。
规格：冻干粉针剂:25mg(5ml)
类别：免疫抑制剂
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条