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1)  lymphocytes tumor infiltrating
肿瘤浸润.淋巴细胞
2)  tumor-infiltrating lymphocytes
肿瘤浸润淋巴细胞
1.
To investigate the mechanisms of hepatic cancer cells inducing apoptosis of tumor-infiltrating lymphocytes (TILs) in vitro, hepatic cancer cells were co-cultured with TILs in different effector-taget ratio.
为了探讨肝癌细胞反击肿瘤浸润淋巴细胞(TIL)的机制,在体外进行肝癌细胞和TIL混合培养后,检测两种细胞FasL、Fas、caspase-8基因的表达情况,以及肿瘤细胞反击时TIL凋亡比例的变化。
2.
Objective To study the expression and significance of CD8~+CD28~+ in gastric carcinoma tumor-infiltrating lymphocytes (TIL) to approach the causes which results in TIL function limits.
目的通过研究CD8~+CD28~+在胃癌肿瘤浸润淋巴细胞(TIL)上的表达及其与肿瘤生物学行为的关系和意义,探讨TIL功能受抑制的原因。
3)  tumor-infiltrating lymphocyte
肿瘤浸润淋巴细胞
1.
Objective: To investigate the optimal efficient ratio of efficacy to target (E/T) and the anti-tumor activity of tumor-infiltrating lymphocytes(TILs) and the mouse s splenocyte lymphocytes stimulated by dendritic cells(DCs) on H22 cells in vitro.
目的:探讨树突状细胞(DC)激活肿瘤浸润淋巴细胞(TIL)和小鼠脾淋巴细胞(小鼠脾LC)的最佳效靶比并观察被有效激活的TIL和小鼠脾LC等对小鼠H22肝癌细胞的体外杀伤作用。
2.
T-lymphocyte subsets and the phenotypes of dendritic cells in tumor-infiltrating lymphocytes (TIL) were detected by flow cytometry (FCM).
方法:用LBP给H22荷瘤小鼠灌胃,连续2周后,测定肿瘤重量,采用流式细胞术检查肿瘤浸润淋巴细胞(tumor-infiltratinglymphocyte,T1L)中T淋巴细胞亚群和DCs的数量,以及协同刺激分子CD80(B7-1)表达的变化。
3.
Objective To determine whether human adenocarcinomas FasL expression is associated with increased apoptotic induction in tumor-infiltrating lymphocyte (TIL) and to provide evidence to support the Fas counterattack theory as a mechanism of immune escape in cancer.
目的 通过对人体肿瘤标本的连续切片 ,测定同一区域肿瘤周边病灶中淋巴细胞上的FasL和肿瘤浸润淋巴细胞凋亡的关系 ,探讨肿瘤免疫逃避的机制。
4)  Tumor infiltrating lymphocyte
肿瘤浸润淋巴细胞
1.
Objective: To investigate the activities of tumor infiltrating lymphocytes(TILs) stimulated by dendritic cells(DCs) on mouse breast cancer cells in vitro.
目的:探讨致敏的树突状细胞(DC)激活的肿瘤浸润淋巴细胞(TIL)体外抗小鼠乳腺癌活性。
5)  Tumor infiltrating lymphocyte
肿瘤浸润性淋巴细胞
1.
Compared with LAK (lymphokine activated killer cells), TIL (tumor infiltrating lymphocyte) has faster proliferation, higher immune activity and stronger killer activity to tumor cells, especially combined with chemotherapy and traditional Chinesemedicine.
肿瘤浸润.淋巴细胞 (tumorinfiltratinglymphocyte,TIL)增殖速度快、免疫活性强 ,比淋巴因子激活的杀伤细胞 (lymphokineactivatedkillercells,LAK)具有更强的特异杀瘤活性 ,与化学治疗及中医中药联用疗效更
6)  Tumor infiltrating lymphocytes
肿瘤浸润性淋巴细胞
补充资料:抗淋巴细胞球蛋白 , 抗淋巴细胞免疫球蛋白,抗人胸腺淋巴细胞球蛋白
药物名称:抗淋巴细胞球蛋白

英文名:Antilymphocyte Globulin

别名:抗淋巴细胞球蛋白 , 抗淋巴细胞免疫球蛋白,抗人胸腺淋巴细胞球蛋白
外文名:Antilymphocyte Globuli ,ALG
适应症:
1.适用于器官移植时的抗免疫排异治疗。用于人的同种异体移植有明显疗效,特别是对肾脏移植的病人。但也有一定局限性,主要是对急性排异期有效,对体液免疫所致的超急性排异无效。与硫唑嘌呤、泼尼松合用可提高脏器移植的成功率。骨髓移植时,供者与受者双方在术前均给以抗淋巴细胞球蛋白,有防止移植物抗宿主反应的作用。 2.自身免疫性疾病。ALG对肾小球肾炎、红斑狼疮、类风湿性关节炎、重症肌无力等自身免疫性疾病有良好疗效,对顽固性皮炎、脉管炎、原发性肝炎、交感性眼炎等也有一定疗效
用量用法:
肌注:马ALG每次每千克体重4~20mg,兔ALG每次每千克体重0.5~1mg,1日1次或隔日1次,14日为1疗程。 静注:马ALG每次每千克体重7~20mg,稀释于50~100ml等渗盐水中,于4~6小时内滴完,输入适量等渗盐水,1日1次。
注意事项:
1.肌注可引起局部疼痛、红肿、发热、荨麻疹等,甚至有过敏性休克,静注也可有短时高热(38~40℃,持续3小时)、发冷,有时伴有关节痛和气短。静滴可见一过性体温升高与寒颤、低血压、心率增快等。一般在1~2小时内消退。 2.过敏体质者禁用,有急性感染者慎用。 3.采用ALG治疗自身免疫性疾病应特别慎重,因长期应用使机体的免疫监管功能降低,给癌变细胞的发展以可乘之机。
规格:冻干粉针剂:25mg(5ml)

类别:免疫抑制剂
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