METHODS: Title compounds (I 1～III 6) were synthesized by phase transfer Wittig reaction and screened by several antitumor models in vitro .

METHODS Electrophilic substitution, aldol condensation, selective reduction, phase transfer Wittig reaction and hydrolysis reaction were used in the synthesis of the title compounds.

Synthesis of (L)-Lactataldehyde and stereoselectivity of its Wittig reaction.;

Synthesis of fluorescent brightener DX.EB based on Wittig reaction;

Aplication of Wittig reaction and the modified method in fluorescent whitener syntheses;

A series of π-conjugated compounds with biphenyl chromophore were synthesized from 4,4'-bis(diethoxy phosphonomethyl)-diphenyl and aromatic aldehydes(or cinnamaldehyde) by Wittig-Horner reaction with alkali-assisted catalysis in DMF solution.

Six novel 2,5-bis[4-(2-arylvinyl)phenyl]-1,3,4-oxadiazoles were designed and synthesized through Wittig-Horner reaction by embedding electron-transporting 1,3,4-oxadiazole in PPV oligomer, which are one kind of blue luminescence materials with highly hole injection, and their chemical structures were also determined to show trans-vinylene character according to IR and 1H NMR spectra.

Natural occurring diene fatty acid ester 7a and its derivatives 7b,7c were easily synthesized in 24%-30% yields by the bis-Wittig reactions of bis-Ylide 2 resulted easily from the reaction of the corresponding bis-phosphonium salt and n-BuLi,with two different aldehydes.