Optimal technical conditions of preparing spherical nitroguanidine(NQ) had been obtained by adopting uniform design experimentation, and the spheral nitroguanidine with higher bulk density had been prepared.

Screening of High Rhamnolipid-producing Mutants Induced by NTG;

Mutagenic effects of NTG on Haematococcus pluvialis;

Screening of a strain with high yield of producing 3-hydroxypropionic acid by NTG combining with UV mutagenesis;

A high yield and stable succinic producing strain S-57 was obtained from the mutation of mucor S-1 treated with ultraviolet ray and nitrosoguanidine (NTG).

Using BM10 strain as original strain for treatment with ultraviolet(UV),microwave(MW),nitrosoguanidine(NTG),diethyl sulfate(DES) and LiCl for mutation,the mutation strains with higher antagonistic activit.

subtilis UN9 were prepared under its optimal formation conditions and mutated multiply by ultraviolet radiation and nitrosoguanidine (NTG).

Ab inito Study on the Isomerization Reaction of Nitroguanidine;

An experimental model in which alkylating agent N methyl N′ nitro N nitroguanidine (MNNG) with low concentration was employed to induce genetic instability of a monkey kidney vero cell line, it was proved that there were changes in the patterns of protein tyrosine residue phosphorylation and the activation of stress activated kinase(JNK/SAPK).