1) claisen-schmidt reaction
Claisen-Schmidt反应
1.
β-nitrostyrene was synthesized by ultrasonic Henry reaction and the accessory ingredient of alcohol Claisen-Schmidt reaction,using benzaldehyde and nitromethane as raw materials.
分别研究了在超声波辅助Henry反应和甲醇助剂存在Claisen-Schmidt反应的条件下由苯甲醛、硝基甲烷合成β-硝基苯乙烯的反应条件,发现Claisen-Schmidt反应条件下收率最高,产率为84%。
2) Schmidt-Claisen reaction
Schmidt-Claisen反应
1.
(E)-3-[4-β-D-Allopyranosyloxyphenyl]acrophenones (3a～3h) with a structure of chalcone were synthesized by Schmidt-Claisen reaction of 4-substituted hypnone with helicid, among which 3c, 3e and 3f are three new compounds.
以豆腐果苷为原料,与4-取代苯乙酮发生Schmidt-Claisen反应,得到一系列查尔酮结构的E-4-β-D-吡喃阿洛糖苷-苯乙烯基-4-取代苯乙酮衍生物3a～3h,其中3c,3e,3f为新化合物。
3) Claisen-Schmidt condensation reaction
Claisen-Schmidt缩合反应
1.
Investigation on activity of Claisen-Schmidt condensation reaction for different substituted benzaldehyde compounds;
不同取代芳醛Claisen-Schmidt缩合反应活性研究
2.
Investigation of Claisen-Schmidt condensation reaction using near-critical water as media indicated that the reaction can be carried out in near-critical water without any added catalyst.
对近临界水中苯甲醛与丙酮的Claisen-Schmidt缩合反应的研究表明,在没有外加任何催化剂的条件下,苯甲醛与丙酮可顺利地发生缩合反应,近临界水在其中兼作溶剂和催化剂,避免了碱催化剂的使用和随后繁杂的中和、分离步骤以及产生废弃盐等弊端。
4) Claisen-Schimidt reaction
Claisen-Schimidt反应
1.
Using helicid as starting material,novel E-(4-β-D-allopyranosyloxyphenyl)-1-(4-substituted phenyl)propenone derivatives(1a ～ 1e) have been synthesized by Claisen-Schimidt reaction with 4-substituted hypnone.
以豆腐果苷为原料,与4-取代苯乙酮发生Claisen-Schimidt反应,得到一系列E-4-β-D-吡喃阿洛糖苷-苯乙烯基-4-取代苯酮衍生物1a～1e,再将1a～1e与邻氨基苯硫酚发生1,4-Michael反应,得到2-(4-β-D-吡喃阿洛糖苷-苯基)-4-芳基-2,3-二氢-1,5-苯并硫氮杂衍生物2a～2e,以上化合物均未见文献报道,其结构经1H NMR,IR,MS加以确证,并对2a～2e进行了药理活性筛选。
5) aza-Claisen reaction
aza-Claisen反应
6) Claisen-Schmidt condensation
Claisen-Schmidt缩合
1.
Piperonylene propanal was synthesized through Claisen-Schmidt condensation reaction in the presence of KF/Al2O3,heliotropin and propanal as reactants.
KF Al2O3作催化剂,催化洋茉莉醛和丙醛进行Claisen-Schmidt缩合反应合成了亚胡椒基丙醛。
2.
A series of substituted-2 -hydroxychalcone in yields of 48%～90% were synthesized by Claisen-Schmidt condensation from substituted 2 -hydroxyhypnone and substituted benzaldehyde under room temperture.
取代-2′-羟基苯乙酮与取代苯甲醛在室温下经过Claisen-Schmidt缩合,合成了一系列取代2′-羟基查尔酮类化合物(3a~3w,其中3d~3w为新化合物),收率48%~90%,其结构经1H NMR和IR表征。
3.
Via Claisen-Schmidt condensation and hydrogenation reaction, raspberry ketone was synthesized by using p-hydroxybenzaldenhyde as the main raw material.
本文以对羟苯甲醛为主要原料,通过Claisen-Schmidt缩合、加氢还原二步反应合成覆盆子酮;根据气味分子结构理论设计、合成了四个覆盆子酮类似物,采用红外光谱、核磁共振及质谱等分析方法对合成产物的结构进行了表征,并经调香师对其进行评香,确定这些化合物具有作为香料的应用前景。
补充资料：Claisen-Schmidt reaction
分子式：
CAS号：
性质：芳香族醛与脂肪族或脂肪芳香族的醛、酮、腈类等在氢氧化钠水溶液或醇钠的催化作用下发生缩合，形成α-及β-不饱和醛、酮或腈，称为克莱森-施密特反应。硝基化合物也可发生类似反应，产物经催化还原即得到在植物碱合成中重要的原料β-苯乙胺类。
CAS号：
性质：芳香族醛与脂肪族或脂肪芳香族的醛、酮、腈类等在氢氧化钠水溶液或醇钠的催化作用下发生缩合，形成α-及β-不饱和醛、酮或腈，称为克莱森-施密特反应。硝基化合物也可发生类似反应，产物经催化还原即得到在植物碱合成中重要的原料β-苯乙胺类。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条