2) Notch signal pathway
Notch信号通路
1.
The Notch signal pathway is a conservative mechanism between cells,which keep the balance of cell proliferation,differentiation and apoptosis,and enlarge and rigidificate molecule difference between cells and determine the cell differentiation.
Notch信号通路作为一种进化上相对保守的细胞相互作用机制,维持着细胞增殖、分化、凋亡之间的平衡,其能够扩大并固化相邻细胞之间的分子差异,对细胞分化命运起决定性作用。
2.
It s pathogenesis is comparatively complicated and recently is focused on abnormality in early genetics,interaction between hemopoietic microenvironment and myeloma cells,NF-κB and Notch signal pathways and drug resistance.
多发性骨髓瘤(mu ltip le myelom a,MM)是一种恶性增殖性疾病,其发病机制十分复杂,近年集中在早期遗传学异常、造血微环境与骨髓瘤细胞的相互作用、NF-κB和Notch信号通路、MM耐药机制几方面,形成了以针对信号通路和骨髓微环境治疗为主的综合治疗框架。
3.
To study the role of Notch signal pathway in the proliferation and differentiation of NSCs.
Notch信号通路对于维持体外培养的神经干细胞增殖有重要的作用。
3) Notch signaling pathway
Notch信号通路
1.
Notch signaling pathway plays a key role in cell development and cell-cell communication in vertebrates and invertebrates,including the regulations of cell fate,migration,differentiation,and proliferation.
Notch信号通路在脊椎动物和无脊椎动物许多组织的发育过程和细胞间通讯中都发挥了关键的作用,包括调控细胞命运,调节细胞迁移,分化和增殖。
2.
Notch signaling pathway regulates multiple stages of thymocyte development.
Notch信号通路在哺乳动物胸腺细胞发育过程的多个阶段发挥关键作用。
3.
Some researches have proved that Notch signaling pathway plays an important role in embryonic blood vessels development and tumor angiogenesis.
研究证实Notch信号通路在胚胎血管发育和肿瘤血管新生过程中起着重要的调控作用,但Notch信号通路是否参与脑缺血后血管新生的调控尚待研究证实。
4) Notch signaling
Notch信号通路
1.
2 5μM DAPT could effectively inhibit Notch signaling.
目的 1以人神经胶质瘤细胞系U251为研究对象,观察γ-分泌酶抑制剂DAPT(Notch信号通路的阻断剂)与TGF-α(Ras/MAPK信号的激动剂)对U251生长增殖的影响。
2.
2,To observe the effect of DAPT on Notch signaling molecules,including Notch1 and Hes1.
目的1、以人神经母细胞瘤细胞系SH-SY5Y为研究对象,利用γ-分泌酶抑制剂DAPT抑制细胞Notch信号通路,观察其对SH-SY5Y细胞增殖的影响。
6) NOTCH-1
NOTCH-1信号通路
1.
NOTCH-1 Signaling Regulates Proliferation and Differentiation of Human Brain Glioma Stem Cells;
NOTCH-1信号通路对脑胶质瘤干细胞增殖与分化调控作用的实验研究
补充资料：[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]
分子式：C16H16ClN3O3S
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条