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1)  Notchsignaling transduction
Notch信号转导
2)  Notch signaling transduction pathway
Notch信号转导通路
3)  Notch/RBP-J signaling pathway
Notch/RBP-J信号转导途径
4)  Notch signal
Notch信号
1.
The proliferation and apoptosis of multiple myeloma (MM) cells were regulated by bone marrow microenvironments in which Notch signal plays important role in mediating cell-cell communication.
Notch信号是骨髓中细胞与细胞之间通讯的主要信号通路之一 ,它对多发性骨髓瘤细胞的调节作用目前并不清楚。
2.
Active Notch signal inhibits the differentiation of HSCs while promotes their expansion,suggesting that ex vivo expansion of hematopoietic progenitor cells could be enhanced by manipulating Notch signal pathway.
Notch受体和配体在造血系统中广泛存在,活化的Notch信号可抑制造血祖细胞的分化而促进其扩增,提示可以通过Notch信号途径实现对造血祖细胞的扩增。
3.
Notch signal is one of the main direct action signal path between cell and cell,and is key point to determine cell fate of organisma multicellularis.
Notch信号是细胞与细胞之间直接作用的主要信号通路之一,并对多细胞生物中细胞命运的决定起关键作用。
5)  Notch signaling
Notch信号
1.
Relationship between the Notch signaling and cardiovascular development;
Notch信号通路与心血管发育的关系
2.
Hypoxia-responsive Notch signaling suppressing protein regulates the in vivo growth of CT26 colon carcinoma cells in mice
具有缺氧反应性的Notch信号抑制蛋白调节鼠结肠癌细胞的体内生长
3.
Notch signaling pathway is an evolutionarily highly conserved mechanism for cell-cell communication, which controls differentiation and proliferation, and plays an important role in embryogenesis and many types of cell fate determination.
Notch信号是一个在进化中高度保守的反映细胞间通讯机制的通路,它调控细胞的分化和增殖,在胚胎发育和细胞命运的决定中发挥重要的作用。
6)  Notch signal pathway
Notch信号通路
1.
The Notch signal pathway is a conservative mechanism between cells,which keep the balance of cell proliferation,differentiation and apoptosis,and enlarge and rigidificate molecule difference between cells and determine the cell differentiation.
Notch信号通路作为一种进化上相对保守的细胞相互作用机制,维持着细胞增殖、分化、凋亡之间的平衡,其能够扩大并固化相邻细胞之间的分子差异,对细胞分化命运起决定性作用。
2.
It s pathogenesis is comparatively complicated and recently is focused on abnormality in early genetics,interaction between hemopoietic microenvironment and myeloma cells,NF-κB and Notch signal pathways and drug resistance.
多发性骨髓瘤(mu ltip le myelom a,MM)是一种恶性增殖性疾病,其发病机制十分复杂,近年集中在早期遗传学异常、造血微环境与骨髓瘤细胞的相互作用、NF-κB和Notch信号通路、MM耐药机制几方面,形成了以针对信号通路和骨髓微环境治疗为主的综合治疗框架。
3.
To study the role of Notch signal pathway in the proliferation and differentiation of NSCs.
Notch信号通路对于维持体外培养的神经干细胞增殖有重要的作用。
补充资料:脉心导敏 ,脉导敏,英他佐明,麦新导明
药物名称:吗多明

英文名:Molsidomine

别名: 吗导敏;吗多明;吗斯酮胺;脉心导敏 ,脉导敏,英他佐明,麦新导明
外文名:Molsidomine
特点:
脉导敏是一种属于亚胺类化合物,其作用与硝酸盐相似。舌下含服1毫克,2~4分钟起作用,可阻止心绞痛发作。口服一次可持续6~7小时,剂量每天3次,每次2毫克。副作用包括头痛、头胀、脸部发热感等,但不多见。
适应症:
防治心绞痛的发作。
用量用法:
口服:1次1~2mg,1日2~3次,发作时舌下含服:1次2mg。喷雾吸入:每次揿吸1~2次(相当于本品0.2~0.4mg),每日次数酌定。
注意事项:
1.一般不良反应可有头痛、面部潮红、眩晕等,停药后可自行消失。 2.低血压、青光眼病人忌用。
规格: 片剂:每片1mg、2mg。 气雾剂:每瓶含42mg(可揿吸200次左右)。





类别:非选择性钙通道阻滞剂||防治心绞痛药
说明:补充资料仅用于学习参考,请勿用于其它任何用途。
参考词条