2) Aurora kinase inhibitor
Aurora激酶抑制剂
1.
Aurora kinase inhibitors are new member of the family of targeted agents.
Aurora激酶抑制剂是分子靶向治疗的新领域,Aurora激酶不仅与肿瘤密切相关,而且Aurora激酶抑制剂也显示了很强的抗肿瘤能力,部分抑制剂都进入了Ⅰ期临床实验。
2.
Recent work indicates that an Aurora kinase inhibitor MK-0457 (VX-680),a small-molecule inhibitor of Aurora kinases A,B,C and BCR-ABL,FLT-3,JAK-2,can block the progression of cell growth cycle,causing apoptosis in a range of human tumors.
近年来研究的一种Aurora激酶抑制剂MK-0457(VX-680),是Aurora激酶A、B、C及BCR-ABL、FLT-3、JAK-2等多种激酶的小分子抑制剂。
4) Aurora kinase
Aurora激酶
1.
Vx-680,a small molecule inhibitor of the Aurora kinases,suppresses head and neck tumor growth in vitro;
Aurora激酶抑制剂VX-680对头颈肿瘤细胞增殖的影响
2.
Aurora kinase,a vital regulator for cellular mitosis affecting the process of cell cycle,is regarded as a new target for the anti-tumor drugs.
Aurora激酶家族是细胞有丝分裂期重要的调节因子,可影响细胞周期进程,是抗肿瘤药物的新靶点。
3.
Recent studies have found aberrant expression of Aurora kinases in a variety of human solid tumors and hematological malignancies,suggesting they are important targets for anti-cancer drugs.
Aurora激酶家族是苏氨酸/丝氨酸激酶,在有丝分裂的染色体排列,分离和胞质分裂中起重要作用。
5) Kinase inhibitor
激酶抑制剂
1.
The feasibility of application of reverse docking method to the selectivity studies of protein kinase inhibitors
探索应用反向对接技术研究蛋白激酶抑制剂选择性的可行性
2.
The signal transduction pathway of multi-target kinase inhibitors as anticancer agents in clinical use or in phase Ⅲ
已上市和部分正在Ⅲ期临床开发中的多靶点激酶抑制剂抑酶谱及信号传导通路分析
3.
A number of diseases are linked to overactivation of protein kinases and a lot of kinase inhibitors have been developed.
由于蛋白激酶的异常激活导致了许多疾病,激酶抑制剂成为当今医药领域的研究热点。
6) protein kinase inhibitor-B(PKIB)
人cAMP依赖型蛋白激酶B抑制剂(PKIB)
补充资料：[3-(aminosulfonyl)-4-chloro-N-(2.3-dihydro-2-methyl-1H-indol-1-yl)benzamide]
分子式：C16H16ClN3O3S
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
分子量：365.5
CAS号：26807-65-8
性质：暂无
制备方法：暂无
用途：用于轻、中度原发性高血压。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条