we constructed eukaryotic expression vector of shRNA specific for STAT1 gene and transfected it into human airway epithelial cells (16HBE) stimulated by IFN-γand detected its interference activity, which will establish a favourable foundation for further study of gene therapy of the inflammation disease like asthma et al.

Effect of cigarette smoke extract on proliferation and cycle of human airway epithelial cell and its FIP200 expression;

Role of glycogen synthase kinase 3 in squamous differentiation of pig airway epithelial cells: A primary study;

Study of IFN-γ gene of rats transfected into airway epithelial cell of rats;

Spatial-temporal distribution of glycogen synthase kinase 3βand adenomatous polyposis coli protein are involved in the injury and repair of airway epithelial cells induced by scratching;

Transfection of recombined rat IFN-γ into rat alveolar macrophage and airway epithelial cells in vitro;

Objective:To explore the activation of extracellular signal-regulated kinase(ERK1/2) in injured airway epithelial cells and its pathological significance.

Construction of recombinant adenovirus vector Ad-elafin for nature antibiotic elafin gene and its expression in primary airway epithelium;

Objective: To investigate the expression of NOS 2 and Fas in airway epithelium, and assay the role of NOS 2 and Fas on pathogenisisin asthmatic guinea pigs.