Advances in the study of A_(2B) adenosine receptor antagonists;

Progression of adenosine receptor in cerebral ischemia;

Increase in amount and affinity of adenosine receptor in rat hippocampal cellular membranes induced by cerebral ischemic preconditioning and its protective effects on the neurons;

Role of protein kinase C in adenosine A1 receptor regulating opening of mitochondria permeability transition pore in hypoxic cardiac myocytes;

Effect of adenosine A1 receptor in the rapid ischemic tolerance induced by pretreatment with single electroacupuncture in rats;

Especially,the A_(3) adenosine receptor plays an important role in regulating cell vitality and growth.

Aim To study the effect of blocking adenosine A_1 receptors on BDNF protein expression and the endoplasmic reticulum(ER) content of the rat hippocampus.

Methods:The influence of the selective adenosine A_1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine(DPCPX)on acetylcholinechloride(ACh)concentration in the rat brain was studied through bioassay of the toad isolated musculus rectus abdominis using the isolated-organ measuring apparatus.