In our model,DNA chain is regarded as freely connecting segments with a bead tethered to the end of the chain.

Studies on the DNA strand breakage as biomarker of exposure to aldehyde pollutants;

Study in vitro on the activity of poly(ADP-ribose)polymerase(PARP)and DNA strand breakage induced by nickel;

DNA strand breakage of human hepatoma cells induced by γ-ray measured using the Comet Assay;

5) in Beijing on micronucleus formation of Balb/c 3T3 cell and DNA strand breaks, were inspected using cytochalasin B-blocked test and single cell electrophoresis method; and their effects on gap junction intercellular communication (GJIC) of Balb/c 3T3 cells were observed through scrape-loading/dye transfer (SL/DT) technique.

The results showed that the deoxyguanosine modification and DNA strand breaks upon the concentration of peroxynitrite.

Objective To investigate DNA strand breaks and micronuclei induced by sodium pentachlorophen (Na-PCP) in different phases and different dosages in vivo.

Factors influencing the stability of triplex DNA;

DNA triple-helix formation is of great potential including selective control of gene expression, site-directed mutagenesis, gene repair, in situ chromosome labelling and other molecular diagnostics, thus the antigene strategy based on triplex DNA offers new therapeutic applications.

Spectra of the Supramolecular Interaction of Neutral Red with Double-stranded DNA in a Neutral Medium;

Objective To study the effect of different immunization methods on the production and pathogenicity of anti-dsDNA antibodies induced by kinetoplast DNA (kDNA) derived from trypanosoma equiperdum (TE) on normal mice.