1) cefuzonam
头孢唑喃
2) cefuzonam sodium
头孢唑喃钠
3) Cefmetazole
头孢美唑
1.
Combination of cefmetazole with ciprofloxacin against 33 strains of extended-spectrum beta-lactamase-resistent bacteria;
头孢美唑与环丙沙星对33株产ESBL菌的体外抗菌活性
2.
The study on the antibacterial activity of cefmetazole combined with gatifloxacin against 33 strains extended-spectrum beta-lactamase production bacteria;
头孢美唑联合加替沙星对33株产超广谱β-内酰胺酶细菌的联合药敏研究
4) cefozopran
头孢唑兰
1.
Imidazo〔1,2-b〕pyridazine is the main intermediate with side chain for synthesis of cephalosporins, it has become a bottle-necking problem for development of cefozopran as its greater difficulty in synthesis.
咪唑并〔1, 2- b〕哒嗪是合成头孢类抗生素的侧链中间体,因合成难度较大,成为国内开发头孢唑兰的瓶颈。
2.
This paper reviews the antimicrobial mechanism,antibacterial spectrum of activity against gram-positive organisms,pharmacological features and clinical indications of cefozopran as well as its clinical efficacy and safety.
综述了第四代头孢菌素类抗生素头孢唑兰的作用机制、抗菌活性、药理学性质及临床应用方面的研究概况,并评估其有效性及安全性,为临床用药提供参考。
3.
6-Chloroimidazo[1,2-b]pyridazine,as an important intermediate of cefozopran,was synthesized from hydrazine hydrate and maleic anhydride through condensation,chlorination,ammonolysis and ring-closing reaction,with the total yield of 65.
以水合肼和马来酸酐为原料,经缩合、氯化、氨解和关环4步反应合成头孢唑兰的中间体6-氯咪唑并[1,2-b]哒嗪,总收率为65。
5) Cefazolin
头孢唑啉
1.
Electrochemical Behavior of Degradation Product of Cefazolin with Silver Microdisk Electrode and Its Application to Analytical Chemistry;
头孢唑啉降解产物在银亚微盘电极上的电化学行为及其测定
2.
Prophylactic Use of Cefazolin for Perioperative Infection in Gynecologic Surgery:A Randomized Controlled Study;
头孢唑啉在妇科围术期预防应用的随机对照研究
3.
Simultaneous determination of cefazolin and baicalin in rabbit serum by HPLC;
高效液相色谱法同时测定家兔血清中头孢唑啉和黄芩苷含量
6) Ceftizoxime
头孢唑肟
1.
Determination of Main Component in Ceftizoxime Sodium for Injection by HPLC;
HPLC法测定注射用头孢唑肟钠中主药的含量
2.
Determination of Serum Ceftizoxime Concentration by HPLC;
高效液相色谱法测定血清头孢唑肟浓度
3.
Comparison of ceftizoxime stability with other 14 β-lactams to β-lactamases;
比较头孢唑肟与其他14种β内酰胺类抗生素对β内酰胺酶的稳定性
补充资料：头孢唑喃
分子式：
CAS号：
性质：半合成第三代头孢菌素，白色至浅黄色结晶性粉末。易溶于水、甲醇，难溶于乙醇，不溶于乙醚。紫外吸收光谱λmax256～260nm(353～362)，旋光度-26°～34°。性能属第三代头孢菌素，特点是增强了抗革兰氏阳性菌活性。抗葡萄球菌属的活性与头孢唑啉相同，比头孢哌酮强2～4倍。对链球菌属与头孢甲肟相同，较头孢哌酮、头孢唑啉强4～8倍以上。抗耐甲氧西林与头孢菌素的金葡菌(MRSA)活性比头孢唑啉强2倍。抗革兰氏阴性杆菌活性相同于或稍逊于头孢甲肟，抗绿脓杆菌活性为头孢哌酮的1/4～1/8。治疗各科感染1389例，有效率为75.6％，细菌清除率为75.8％．2354例中有4.2％出现不良反应，主要为药疹与胃肠道症状。
CAS号：
性质：半合成第三代头孢菌素，白色至浅黄色结晶性粉末。易溶于水、甲醇，难溶于乙醇，不溶于乙醚。紫外吸收光谱λmax256～260nm(353～362)，旋光度-26°～34°。性能属第三代头孢菌素，特点是增强了抗革兰氏阳性菌活性。抗葡萄球菌属的活性与头孢唑啉相同，比头孢哌酮强2～4倍。对链球菌属与头孢甲肟相同，较头孢哌酮、头孢唑啉强4～8倍以上。抗耐甲氧西林与头孢菌素的金葡菌(MRSA)活性比头孢唑啉强2倍。抗革兰氏阴性杆菌活性相同于或稍逊于头孢甲肟，抗绿脓杆菌活性为头孢哌酮的1/4～1/8。治疗各科感染1389例，有效率为75.6％，细菌清除率为75.8％．2354例中有4.2％出现不良反应，主要为药疹与胃肠道症状。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条