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1)  CPIZ
头孢咪唑
2)  cefpimizole sodium
头孢咪唑钠
3)  Cefathiamidine
头孢硫咪
1.
The Intervention of Cefathiamidine on C-reaction Protein in Infants with Pneumonia;
头孢硫咪对婴幼儿肺炎C-反应蛋白的干预
4)  Cefquinome
头孢喹咪
5)  Cefmetazole
头孢美唑
1.
Combination of cefmetazole with ciprofloxacin against 33 strains of extended-spectrum beta-lactamase-resistent bacteria;
头孢美唑与环丙沙星对33株产ESBL菌的体外抗菌活性
2.
The study on the antibacterial activity of cefmetazole combined with gatifloxacin against 33 strains extended-spectrum beta-lactamase production bacteria;
头孢美唑联合加替沙星对33株产超广谱β-内酰胺酶细菌的联合药敏研究
6)  cefozopran
头孢唑兰
1.
Imidazo〔1,2-b〕pyridazine is the main intermediate with side chain for synthesis of cephalosporins, it has become a bottle-necking problem for development of cefozopran as its greater difficulty in synthesis.
咪唑并〔1, 2- b〕哒嗪是合成头孢类抗生素的侧链中间体,因合成难度较大,成为国内开发头孢唑兰的瓶颈。
2.
This paper reviews the antimicrobial mechanism,antibacterial spectrum of activity against gram-positive organisms,pharmacological features and clinical indications of cefozopran as well as its clinical efficacy and safety.
综述了第四代头孢菌素类抗生素头孢唑兰的作用机制、抗菌活性、药理学性质及临床应用方面的研究概况,并评估其有效性及安全性,为临床用药提供参考。
3.
6-Chloroimidazo[1,2-b]pyridazine,as an important intermediate of cefozopran,was synthesized from hydrazine hydrate and maleic anhydride through condensation,chlorination,ammonolysis and ring-closing reaction,with the total yield of 65.
以水合肼和马来酸酐为原料,经缩合、氯化、氨解和关环4步反应合成头孢唑兰的中间体6-氯咪唑并[1,2-b]哒嗪,总收率为65。
补充资料:头孢咪唑
分子式:
CAS号:

性质:为半合成的第三代头孢菌素。其单钠盐为白色或微黄白色结晶性粉末,无臭或微臭,熔点197~210℃,旋光度 -28.2°(c=0.5,水)。易溶于水,难溶于甲醇,几乎不溶于乙醇、醚和丙酮。对革兰氏阳性菌和阴性菌及厌氧菌有广谱抗菌活性,尤对绿脓杆菌抗菌作用强。对β-内酰胺酶高度稳定,对TEM型青霉素酶也稳定。

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