1) arabinonucleoside
阿糖苷
2) Adenine arabinoside
阿糖腺苷
1.
Objective:In order to establish an effective process to produce adenine arabinoside(ara-A),enzymatic synthesis of ara-A catalyzed by whole cells of Enterobacter aerogenes was studied.
目的:为了开发一种生产阿糖腺苷的有效方法。
3) vidarabine
阿糖腺苷
1.
The content of vidarabine(Ara-A)and the encapsulation percen-tage of vidarabine(Ara-A) in liposome (EN%)were determined with ultravioletspectrophotometry and HPLC.
利用紫外分光光度法和高效液相色谱法测定阿糖腺苷(Ara-A)脂质体的含量及包封率(EN%)。
2.
With the assistance of microwave irradiation,vidarabine is afforded in high yields through 6 steps,starting with adenosine,which can be obtained cheaply and conveniently.
在微波辅助下,以廉价的腺苷为原料,经6步反应,以较高产率合成了具有重要生理活性的阿糖腺苷。
3.
Methods 198 subjects were randomized into two groups:control group in which 98 cases were treated by Vidarabine Injection and treatment group in which 100 cases were treated by Vidarabine Injection and Chinese herbs.
方法将198例患者随机分为治疗组(100例)和对照组(98例),两组均采用阿糖腺苷和对症治疗,治疗组同时辨证加用中药,观察两组临床疗效。
4) Ara-C
阿糖胞苷
1.
Study on mechanism of apoptosis induced by Ara-C in leukemia HL-60 cells;
阿糖胞苷诱导HL-60细胞凋亡的分子机制探讨
2.
Effects of Ara-C on proliferation/apoptosis and bcl-2 gene expression of HL60 cell;
阿糖胞苷对HL60细胞增殖和凋亡及bcl-2基因表达的影响
3.
The mechanisms of inhibitory effect of Ara-C and bufalin on human leukemia cells;
阿糖胞苷及蟾蜍灵对HL-60细胞增殖抑制和诱导凋亡的研究
5) Cytosine arabinoside
阿糖胞苷
1.
Pufferfish type Ⅰ collagen extract prevented and cured myelosuppression induced by cyclophosphamide or diamminedichloroplatinum or cytosine arabinoside in mice;
河鲀Ⅰ型胶原蛋白提取物防治环磷酰胺、顺铂或阿糖胞苷诱发小鼠骨髓抑制的研究
2.
Treatment of arsenic and cytosine arabinosideon refractory leukemia;
三氧化二砷联合大剂量阿糖胞苷治疗难治性白血病(附117例报告)
3.
(-)-Epigallocatechin-3-gallate enhances anti-tumor effect of cytosine arabinoside on HL-60 cells;
(-)表没食子儿茶素没食子酸酯增强阿糖胞苷对HL-60细胞的抗肿瘤活性
6) cytarabine
阿糖胞苷
1.
Study on the preparation of cytarabine poly-alkyl-α-cyanoacrylate nanoparticles;
正交设计优选阿糖胞苷聚氰基丙烯酸正丁酯纳米粒制备工艺
2.
Research progress on pharmacokinetics of fludarabine and its synergistic effect with cytarabine;
氟达拉滨的药代动力学及其与阿糖胞苷协同作用的研究进展
3.
The release characteristics in vitro of cytarabine (Ara-C) poly-alkyl-acyanoacrylate lyophilized nanoparticles for injection;
阿糖胞苷聚氰基丙烯酸正丁酯纳米粒冻干针剂体外释药特性
补充资料：阿糖苷
分子式：
CAS号：
性质：核苷的结构类似物，DNA合成抑制剂，用于抗病毒或抗肿瘤治疗。其与核苷的差别在于糖的组成部分为阿拉伯呋喃糖，C-2羟基与碱基为顺式结构。阿糖胞苷可抑制CDP还原为dCDP而抑制DNA合成。阿糖腺苷在体内受激酶作用磷酸化为阿糖腺三磷后抑制DNA聚合酶，且对病毒DNA聚合酶的亲和性高于宿主细胞，因而对抑制病毒增殖有较高选择性。阿糖胞苷在体内脱氨后转变为无活性尿嘧啶衍生物。阿糖腺苷脱氨后则转变为无活性的次黄嘌吟衍生物。由于阿糠尿苷、阿糖胸苷等作为天然嘧啶类似物在各种海绵中被发现，故各种阿糖苷也常称为相应的海绵核苷。
CAS号：
性质：核苷的结构类似物，DNA合成抑制剂，用于抗病毒或抗肿瘤治疗。其与核苷的差别在于糖的组成部分为阿拉伯呋喃糖，C-2羟基与碱基为顺式结构。阿糖胞苷可抑制CDP还原为dCDP而抑制DNA合成。阿糖腺苷在体内受激酶作用磷酸化为阿糖腺三磷后抑制DNA聚合酶，且对病毒DNA聚合酶的亲和性高于宿主细胞，因而对抑制病毒增殖有较高选择性。阿糖胞苷在体内脱氨后转变为无活性尿嘧啶衍生物。阿糖腺苷脱氨后则转变为无活性的次黄嘌吟衍生物。由于阿糠尿苷、阿糖胸苷等作为天然嘧啶类似物在各种海绵中被发现，故各种阿糖苷也常称为相应的海绵核苷。
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参考词条