1) Toll-like receptor signaling
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Toll样受体传导途径
2) Toll-like receptor
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Toll样受体
1.
Advancement of the relationship between gene polymorphisms of Toll-like receptors and infectious diseases;
Toll样受体及其基因多态性与感染性疾病关系的研究进展
2.
Change of toll-like receptor mRNA expression in peritoneal macrophages of immunosuppressed mice;
免疫抑制宿主巨噬细胞Toll样受体的表达变化
3.
Effect of Guizhi Tang drug serum on the expression of Toll-like receptors and downstream signaling components in RAW 264.7 cells;
桂枝汤含药血清对小鼠巨噬细胞Toll样受体3、4型及其下游信号转导通路元件的影响
3) toll like receptor
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Toll样受体
1.
Toll like receptor (TLR) belong to animal pattern recognition receptor family.
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Toll样受体(TLR)蛋白家族属于动物模式识别受体家族。
2.
By far,ten toll like receptors were found in human and mammalian.
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Toll样受体是一类在进化中高度保守的Ⅰ型跨膜蛋白,识别病原体相关分子模式,为先天性免疫的重要成分,同时在机体特异性免疫过程中也起着关键性作用。
3.
Objective:To investigate the regulatory effects of tumor necrosis factor-α(TNF-α)and interferon-γ(IFN-γ)on the expression of Toll like receptor(TLR)gene in human basophils.
目的:探讨肿瘤坏死因子α(TNFα)和干扰素γ(IFNγ)对人嗜碱性粒细胞中Toll样受体(TLR)基因表达的调节作用。
4) Toll-like receptors
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Toll样受体
1.
Helicobacter pylori infection and Toll-like receptors;
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幽门螺杆菌感染与Toll样受体
2.
Signal transduction pathway mediated by Toll-like receptors and their relations with infectious eye disease;
Toll样受体介导的信号通路及其与眼部感染性疾病的关系
3.
Research advances in Toll-like receptors and aute lung injury;
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Toll样受体与急性肺损伤研究进展
5) TLR
![点击朗读](/dictall/images/read.gif)
Toll样受体
1.
Toll-like receptors (TLRs),one of the most important PRRs (pattern recognizing receptors), can tigger the intracellular signaling transduction to induce the innate immunity, meanwhile be involved in regulating bacteria-associated cellular actin cytoskeleton rearrangement.
烟曲霉侵染宿主细胞时伴有明显的细胞肌动蛋白骨架重排,而重要模式识别受体PRRs(pattern recognition receptors)之一,Toll样受体(Toll-like receptors,TLR)参与调节病原细菌诱导的宿主细胞肌动蛋白骨架重排,其中TLR2和TLR4两亚型可以识别烟曲霉的病原相关分子模式PAMP(pathogen-assosiated molecular patterns),并诱发炎症因子表达等一系列效应信号,在宿主细胞抗烟曲霉天然免疫中发挥重要作用,但在烟曲霉内化侵入过程中TLR能否特异性介导细胞肌动蛋白骨架重排尚不清楚。
2.
TLR4,the major receptor for LPS,was found to be involved in LPS signaling transduction and to have a close relationship with endotoxin tolerance.
Toll样受体4(Toll-like receptor-4,TLR4)作为脂多糖(LPS)的主要受体,参与LPS信号的跨膜转导,与LPS耐受密切相关。
3.
Human Toll-like receptors expressed on the surface of cells have been reported so far, numbered from TLR1 to TLR10.
目前已经发现了10个存在于人细胞表面的Toll样受体(TLR1-10),并确定了与之相对应的大部分配体。
6) TLRs
![点击朗读](/dictall/images/read.gif)
Toll样受体
1.
TLRs(Toll-like receptors)was a kind of natural receptors which was found in recent years.
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Toll样受体(TLRs)是近年发现的一组天然受体,宿主能通过TLRs蛋白识别大量病原体相关结构:如细菌脂多糖(LPS)、病毒RNA、CPG-DNA以及鞭毛蛋白等。
2.
Toll-like receptors (TLRs), the best-characterized receptors among the pattern recognition receptors (PRRs), recognize a diverse range of pathogen associated molecular patterns and play a critical role in antimicrobial host defense.
Toll样受体是目前研究最清楚的一类模式识别受体,它能识别多种病源微生物相关的分子模式,并在机体抗感染免疫中发挥重要作用。
3.
Toll-like receptors (TLRs) and RIG-I like receptors (RLRs) are two classes of pattern recogni-tion receptors (PRRs) in host cells.
Toll样受体(Toll-like receptors,TLRs)和RIG-I样受体(RIG-I like receptors,RLRs)为宿主细胞识别病毒的两种重要模式受体(pattern recognition receptors,PRRs)。
补充资料:感觉传导途径 3痛觉、温度觉传入途径示意图
李瑞端绘
[图]
![图](/picture/bkimg/ch_8/8_508_20_0.jpg)
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