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1)  Toll-like receptor 5
Toll样受体5
1.
The expression of Toll-like receptor 5 in the lung tissues of rats with acute lung injury induced by flagellin;
Toll样受体5在鞭毛蛋白致大鼠急性肺损伤中的表达研究
2.
Objective To investigate the association of single-nucleotide polymorphisms in toll-like receptor 5 and 9 genes and rheumatic heart disease.
研究目的探讨Toll样受体5和9基因单核苷酸多态性与风湿性心脏病的相关性。
2)  Toll-like receptor
Toll样受体
1.
Advancement of the relationship between gene polymorphisms of Toll-like receptors and infectious diseases;
Toll样受体及其基因多态性与感染性疾病关系的研究进展
2.
Change of toll-like receptor mRNA expression in peritoneal macrophages of immunosuppressed mice;
免疫抑制宿主巨噬细胞Toll样受体的表达变化
3.
Effect of Guizhi Tang drug serum on the expression of Toll-like receptors and downstream signaling components in RAW 264.7 cells;
桂枝汤含药血清对小鼠巨噬细胞Toll样受体3、4型及其下游信号转导通路元件的影响
3)  toll like receptor
Toll样受体
1.
Toll like receptor (TLR) belong to animal pattern recognition receptor family.
Toll样受体(TLR)蛋白家族属于动物模式识别受体家族。
2.
By far,ten toll like receptors were found in human and mammalian.
Toll样受体是一类在进化中高度保守的Ⅰ型跨膜蛋白,识别病原体相关分子模式,为先天性免疫的重要成分,同时在机体特异性免疫过程中也起着关键性作用。
3.
Objective:To investigate the regulatory effects of tumor necrosis factor-α(TNF-α)and interferon-γ(IFN-γ)on the expression of Toll like receptor(TLR)gene in human basophils.
目的:探讨肿瘤坏死因子α(TNFα)和干扰素γ(IFNγ)对人嗜碱性粒细胞中Toll样受体(TLR)基因表达的调节作用。
4)  Toll-like receptors
Toll样受体
1.
Helicobacter pylori infection and Toll-like receptors;
幽门螺杆菌感染与Toll样受体
2.
Signal transduction pathway mediated by Toll-like receptors and their relations with infectious eye disease;
Toll样受体介导的信号通路及其与眼部感染性疾病的关系
3.
Research advances in Toll-like receptors and aute lung injury;
Toll样受体与急性肺损伤研究进展
5)  TLR
Toll样受体
1.
Toll-like receptors (TLRs),one of the most important PRRs (pattern recognizing receptors), can tigger the intracellular signaling transduction to induce the innate immunity, meanwhile be involved in regulating bacteria-associated cellular actin cytoskeleton rearrangement.
烟曲霉侵染宿主细胞时伴有明显的细胞肌动蛋白骨架重排,而重要模式识别受体PRRs(pattern recognition receptors)之一,Toll样受体(Toll-like receptors,TLR)参与调节病原细菌诱导的宿主细胞肌动蛋白骨架重排,其中TLR2和TLR4两亚型可以识别烟曲霉的病原相关分子模式PAMP(pathogen-assosiated molecular patterns),并诱发炎症因子表达等一系列效应信号,在宿主细胞抗烟曲霉天然免疫中发挥重要作用,但在烟曲霉内化侵入过程中TLR能否特异性介导细胞肌动蛋白骨架重排尚不清楚。
2.
TLR4,the major receptor for LPS,was found to be involved in LPS signaling transduction and to have a close relationship with endotoxin tolerance.
Toll样受体4(Toll-like receptor-4,TLR4)作为脂多糖(LPS)的主要受体,参与LPS信号的跨膜转导,与LPS耐受密切相关。
3.
Human Toll-like receptors expressed on the surface of cells have been reported so far, numbered from TLR1 to TLR10.
 目前已经发现了10个存在于人细胞表面的Toll样受体(TLR1-10),并确定了与之相对应的大部分配体。
6)  TLRs
Toll样受体
1.
TLRs(Toll-like receptors)was a kind of natural receptors which was found in recent years.
Toll样受体(TLRs)是近年发现的一组天然受体,宿主能通过TLRs蛋白识别大量病原体相关结构:如细菌脂多糖(LPS)、病毒RNA、CPG-DNA以及鞭毛蛋白等。
2.
Toll-like receptors (TLRs), the best-characterized receptors among the pattern recognition receptors (PRRs), recognize a diverse range of pathogen associated molecular patterns and play a critical role in antimicrobial host defense.
Toll样受体是目前研究最清楚的一类模式识别受体,它能识别多种病源微生物相关的分子模式,并在机体抗感染免疫中发挥重要作用。
3.
Toll-like receptors (TLRs) and RIG-I like receptors (RLRs) are two classes of pattern recogni-tion receptors (PRRs) in host cells.
Toll样受体(Toll-like receptors,TLRs)和RIG-I样受体(RIG-I like receptors,RLRs)为宿主细胞识别病毒的两种重要模式受体(pattern recognition receptors,PRRs)。
补充资料:5-羟色胺受体阻断剂
分子式:
CAS号:

性质:5-羟色胺(5-HT)是重要的神经递质,也是一种自身活性物质。5-HT通过与靶细胞膜上的5-HT受体结合并诱发生物效应。5-HT受体可分为5-HT1A,5-HT1B,5-HT1C,5-HT2,5-HT3。5-HT受体阻断药大致有以下几类,(1)麦角酸的衍生物如麦解酰二乙胺等;(2)组胺H1受体阻断药如赛庚啶等;(3)吩噻嗪类如氯丙嗪等;(4)肾上腺素α-受体阻断药如酚苄明等。常用于实验室研究、较为特异的5-HT受体阻断剂有麦角苄脂、米安色林、苯噻啶等。

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