1) AE-active ester
AE-活性酯
1.
The synthetic technique of AE-active ester is studied in this paper.
研究了AE-活性酯的合成工艺。
2.
AE-active ester [S-2-Benzothiazolyl 2-amino-alpha-(methoxyimino)-4-thiazolethiol acetate] is an important intermediate of many third and fourth generation cephalosporin antibiotics.
本文研究了头孢菌素类抗生素医药中间体AE-活性酯的合成工艺,通过实验确定了最优反应条件,提高了产品质量和收率;通过量子化学计算对AE-活性酯进行密度泛函理论研究,确定其平衡几何构型,分析电荷分布、前沿轨道成分、振动频率等,为头孢菌素类抗生素的定量构效关系等相关理论研究提供有价值的参考。
2) AE active ester
AE活性酯
1.
Cefotaxime acid was synthesized by 7-ACA and AE active ester,the yield was 90%.
7-氨基头孢烷酸和2-甲氧亚氨基-2-(2-氨基-4-噻唑基)-(z)-硫代乙酸苯胼噻唑酯(AE活性酯)发生酰化反应生成头孢噻肟酸,收率90%。
3) AE characteristic
AE特性
4) esterase activity
酯酶活性
1.
Copper concentrations required to inhibit esterase activity of M.
当微囊藻初始细胞密度从103上升到105cells·ml-1时, 24h Cu2+处理后微囊藻酯酶活性的EC50值从4。
2.
By determination of esterase activity in cell fractions gated by FSC(an indicator of the cell volume),it was shown that the resistance to metal ion was improved as the cell vol.
将同一种群的栅藻细胞按其体积大小(FSC参数)分为不同组分,在暴露于毒物后分析不同组分细胞的酯酶活性。
3.
S40Q enhanced the esterase activity by 20% when p-nitrophenyl butylate was used as the substrate;S40G increased the esterase activity by 30% when p-nitrophenyl valerate was used as the substrate.
利用overlapping PCR技术对甘蔗叶灼病解毒蛋白-AlbD酶S40关键位点进行饱和突变,共获得19种突变子,并测试不同突变子的脱毒活性和酯酶活性。
5) active ester
活性酯
1.
Korean LG exploited a novel active ester-DAMA, and it may be substituted active ester-AE by DAMA.
韩国LG公司开发出新型活性酯DAMA ,可以替代AE 活性酯 ,而在我国目前还没有大规模的生产和应用。
2.
In this study the swainsonine was synthesized with active ester,which was prepared by 2 bromine acetic acid,to obtain white powder.
用溴乙酸制备的活性酯与苦马豆素反应 ,产物真空干燥后得到白色粉末状物 ,产率为 77%。
3.
Active ester 8 was prepared creatively and used in the synthesis of ceforanide.
本文创造性地合成了新活性酯8,继而由活性酯8顺利地完成了头孢雷特合成,该法可操作性良好,收率较高,适于大规模制备头孢雷特。
6) activated thioester
活性硫酯
1.
Ceftazidime activated thioester, ( Z ) 2 amino α [[2 ( t butoxy) 1,1 dimethyl 2 oxoethoxy]imino] 4 thiazoleacetic acid 2 benzothiazolyl thioester, was prepared from ethyl ( Z ) 2 (2 aminothiazol 4 yl) 2 hydroxyimino acetate via etherization, selective hydrolyzation and esterification, and the structures of all compounds were confirmed by 1HNMR.
以 2 -氨基 - α-羟亚氨基 - 4 -噻唑乙酸乙酯为原料 ,经过醚化、选择性水解及酯化等反应 ,合成了头孢他啶侧链酸活性硫酯 (Z) - 2 -氨基 - α- [[2 - (叔丁氧基 ) - 1,1-二甲基 - 2 -氧代乙氧基 ]亚氨基 ]- 4 -噻唑乙酸 - 2 -苯并噻唑硫酯。
补充资料：AE-活性酯
分子式：C13H10N3O2S3
分子量：350
CAS号：80756-85-0
性质：淡黄色结晶粉末。
制备方法：暂无
用途：用于制造头孢噻肟、头孢三嗪、头孢曲松、头孢他美酯等先锋类药。
分子量：350
CAS号：80756-85-0
性质：淡黄色结晶粉末。
制备方法：暂无
用途：用于制造头孢噻肟、头孢三嗪、头孢曲松、头孢他美酯等先锋类药。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条