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1)  abdominal pain and alvi profluvium
腹痛腹泻
2)  Diarrhea [英][,daiə'riə]  [美][,daɪə'riə]
腹泻
1.
Investigation and Analysis on Three Outbreaks of Diarrhea Associated With Secondary Water Supply;
三起因二次供水引发的腹泻病暴发调查分析
2.
Prickling on hands,feet,and nipples as well as diarrhea after sorafenib use;
索拉菲尼引起手、足、乳头刺痛和腹泻
3.
Analysis of Pathogens on Infantile Diarrhea from 56905 Cases;
婴幼儿腹泻病原体检测结果分析
3)  diarrhoea [英][,daɪə'rɪə]  [美]['daɪə'riə]
腹泻
1.
The report of 65 examples about using alleviates fever dispels for the spleen to treat the young child autumn diarrhoea;
清热祛湿健脾法治疗小儿秋季腹泻65例
2.
Clinical Characteristic of 236 Inpatients with Antibiotic-associated Diarrhoea;
住院患者抗生素相关性腹泻236例临床分析
3.
An investigation of human rotavirus infection in 2462 infantile diarrhoea;
2462例婴幼儿急性腹泻轮状病毒感染情况调查
4)  Abdominal Pain
腹痛
1.
Right Lower Quadrant Abdominal Pain, Vomiting, Hematochezia and Hepatic Tumor;
右下腹痛、呕吐、便血、肝脏肿块
2.
Blastocystis hominis infection in children with diarrhea and abdominal pain: clinical analysis of 28 cases;
儿童腹痛、腹泻人群中人芽囊原虫的检测:附28例分析
3.
Analysis of misdiagnosis of 10 children with nephrydrosis with abdominal pain as chief manifestation;
以腹痛为主的小儿肾盂积水10例误诊分析
5)  Bellyache [英]['belieɪk]  [美]['bɛlɪ'ek]
腹痛
1.
Analysis of Misdiagnosis of 30 Cases with Acute Bellyache;
30例急性腹痛误诊分析
2.
The remedial observation of the patient whith symptomatic but non-signed bellyache;
有症状无体征的腹痛患者的治疗性观察
6)  Chronic diarrhea
慢性腹泻
1.
Clinial Analysis of 78 children with chronic diarrhea;
78例慢性腹泻临床分析
2.
Prevention of chronic diarrhea caused by infections;
感染所致慢性腹泻的防治
补充资料:苯丁哌胺,腹泻啶
分子式:C29H33ClN2O2
分子量:477.04
CAS号:53179-11-6

性质:该品常用其盐酸盐(C29H33CIN2O2·HCL[34552-83-5])、哌丁胺盐酸为白色至微黄色结晶性粉末,熔点222-223℃。易溶于甲醇、氯仿、冰醋酸,溶于乙醇、DMF,难溶于水、异丙醇、丙酮,不溶于乙醚。

制备方法:以二苯乙腈为原料,在氨基钠存在下与环氧乙烷反应后用盐酸水解,再在室温下用48%HBr-HAc开环,经氯化、二甲胺化后与4-对氯苯基-4-羟基哌啶在甲基异丁基酮及碳酸钠存在下缩合制得洛哌丁胺。以二苯乙腈计,总收率13.4%。

用途:洛哌丁胺为苯基哌啶类止泻药,具有长效作用,用于治疗功能性腹泻以及因胃肠切除或肠器质性损害等引起腹泻,疗效甚佳。小鼠口服LD50为105mg/kg,大鼠(7d)为185mg/kg。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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