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1)  acute diarrhea
急性腹泻
1.
Effect of antibacterial agent and nonantibacterial agent to treat acute diarrhea;
急性腹泻抗菌药物和非抗菌药物的疗效观察
2.
Effects of Saccharomyces boulardii in children with acute diarrhea;
布拉酵母菌治疗儿童急性腹泻的多中心随机对照研究
3.
Evidence based management of childhood acute diarrhea;
儿童急性腹泻治疗的循证评价
2)  diarrhea [英][,daiə'riə]  [美][,daɪə'riə]
急性腹泻
1.
Comparison of therapeutic effects of retention-enema of two drugs in the treatment of infant acute diarrhea;
两种药物保留灌肠治疗婴幼儿急性腹泻效果比较
2.
In this study, we examined 1,093 stool specimens collected in 1998~1999 rotavirus season of 8 regions in China from children with diarrhea.
1998~ 1999年在中国 8个城市 (长春、秦皇岛、北京、杭州、福州、广州、成都、昆明 )采集了急性腹泻患儿的 10 93份非细菌性腹泻粪便标本 ,先进行A组轮状病毒(HRV)的筛选 ,其中阳性标本 433份 (39 6 % ) ,电泳型长型占优势 (96 % )。
3.
Aim: Clinical observation was made on the therapeutic effects of Hua Te Ling developed by the Pharmaceutical Research Center of the hospital for the treatment of acute diarrhea.
目的 :评价我院药研中心研制的新型消化道粘膜保护剂———华特灵治疗急性腹泻的效果。
3)  Acute and chronic diarrhea
急慢性腹泻
1.
The efficacy of Laolining capsule in treatment of 70 patients of acute and chronic diarrhea;
酪立宁胶囊治疗急慢性腹泻70例
4)  acute diarrhea
急性腹泻病
1.
Objective:To study the clinical condition and pathogenic characteristics of acute diarrhea disease among military personnel during military field exercise,thus to provide reference basis for making some measures to prevent and control the disease.
目的 :了解部队野外驻训期间发生急性腹泻病的临床情况及病原特点 ,为部队制订防治措施提供参考依据。
5)  acute diarrhoeal disease
急性腹泻症
6)  acute infectious diarrhea
急性感染性腹泻
1.
Clinical study of Jiuxiang Zhixie enteric-coated tablets for acute infectious diarrhea of damp-heat syndrome;
九香止泻肠溶片治疗湿热型急性感染性腹泻临床研究
2.
Clinical study of rifaximin in 45 patients with acute infectious diarrhea;
利福昔明治疗急性感染性腹泻45例临床观察
3.
Effectiveness and safety of rifaximin capsule in the treatment of acute infectious diarrhea and determination its plasma concentration;
利福昔明胶囊对急性感染性腹泻的疗效和安全性及其血药浓度测定
补充资料:苯丁哌胺,腹泻啶
分子式:C29H33ClN2O2
分子量:477.04
CAS号:53179-11-6

性质:该品常用其盐酸盐(C29H33CIN2O2·HCL[34552-83-5])、哌丁胺盐酸为白色至微黄色结晶性粉末,熔点222-223℃。易溶于甲醇、氯仿、冰醋酸,溶于乙醇、DMF,难溶于水、异丙醇、丙酮,不溶于乙醚。

制备方法:以二苯乙腈为原料,在氨基钠存在下与环氧乙烷反应后用盐酸水解,再在室温下用48%HBr-HAc开环,经氯化、二甲胺化后与4-对氯苯基-4-羟基哌啶在甲基异丁基酮及碳酸钠存在下缩合制得洛哌丁胺。以二苯乙腈计,总收率13.4%。

用途:洛哌丁胺为苯基哌啶类止泻药,具有长效作用,用于治疗功能性腹泻以及因胃肠切除或肠器质性损害等引起腹泻,疗效甚佳。小鼠口服LD50为105mg/kg,大鼠(7d)为185mg/kg。

说明:补充资料仅用于学习参考,请勿用于其它任何用途。
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