By changing the malor ratio of hydrophilic and hydrophobic segement, a series of novel amphiphilic graft polyphosphazenes were synthesized via thermal ring-opening polymerization and subsequent two-step substitution reaction of hydrophilic methoxy polyethylene glycol (MPEG) and hydrophobic ethyl tryptophan (EtTrp).

OBJECTIVE To synthesize polymeric micelles based on amphiphilic polyphosphazenes, investigate their physicochemical properties, study their loading capability to adriamycin (ADR) and their intracellular uptake by tumor cells.

Thermosensitive Polyphosphazenes and its Applications in Drug-Delivery;

New Type of Biodegradable Polymer Used in Medical —— Polyphosphazenes;

Synthesis and Properties of Novel Biodegradable and Electroactive Polyphosphazenes

Study on the Synthesis of Polyphosphazenes and Their Surfaces;

A series of amino acid ester substituted and mixed-substituted polyphosphazenes have been prepared by nucleophilic substitution of poly(dichlorophosphazene) with various amino acid esters.

An amphiphilic polymer,acryl amide(AM)/vinyl acetate(VAc)/butyl acrylate(BA)was synthesized with the effects of amount of AM as well as the ratio between VAc and BA on surface tension,stability against centrifugation,emulsifying power and foaming power of the product examined.