1) Renal tubulointerstitial inflammation and fibrosis
肾间质炎症和纤维化
2) renal interstitial fibrosis
肾间质纤维化
1.
Dilingdan Decoction prevents renal interstitial fibrosis in a rat model of unilateral ureteral obstruction;
地灵丹汤对单侧输尿管梗阻大鼠模型肾间质纤维化的防治作用
2.
Effect of the specific inhibitor of NF-κB on renal interstitial fibrosis in unilateral ureteral obstruction rat models;
特异性NF-κB抑制剂对单侧输尿管梗阻大鼠肾间质纤维化的治疗作用
3.
The Protective Effect of Goralatide on Renal Interstitial Fibrosis of Unilateral Ureteral Obstruction(UUO) Rats;
戈雷拉肽对单侧输尿管梗阻大鼠模型肾间质纤维化的保护作用
3) Renal tubulointerstitial fibrosis
肾间质纤维化
1.
Role of PDGF and PDGFR in murine renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction (UUO);
PDGF及PDGFR在大鼠肾间质纤维化过程中的作用
2.
The relationship between IGF-1 and renal tubulointerstitial fibrosis in 5/6 nephrectomy rats;
IGF-1与实验性慢性肾衰竭大鼠肾间质纤维化的关系
3.
Expression of p-Smad2/3 and smad7 in experimental renal tubulointerstitial fibrosis rat model;
p-Smad2/3、Smad7在大鼠实验性肾间质纤维化模型中的表达
4) tubulointerstitial fibrosis
肾间质纤维化
1.
Effect of Shenluotong on pathology and system of MMP-1/TIMP-1 in rats with tubulointerstitial fibrosis;
肾络通对肾间质纤维化实验大鼠病理及基质金属蛋白酶系统的影响
2.
Purpose To observe whether hypoxia exists in the obstructed kidney of unilateral ureteral obstruction(UUO) rat model and its distribution relationship with tubulointerstitial fibrosis.
目的证实结扎致单侧输尿管梗阻(UUO)大鼠模型梗阻侧肾脏是否存在低氧,不同时间点低氧的特点及低氧与肾间质纤维化的关系。
3.
Objective: To study the effect of Qihong decoction on bcl-2 expression in renal cortex of model rats with tubulointerstitial fibrosis.
方法:采用单侧输尿管结扎致肾间质纤维化大鼠模型,将大鼠随机分为4组:假手术组、模型组、中药芪红合剂组、依那普利组,术后10d处死各组大鼠,收集血清测定尿素氮(BUN)、血肌酐(Cr)水平,结扎侧肾组织行HE、Masson染色,Masson染色分析肾间质纤维化程度,免疫组化半定量检测各组大鼠肾组织中bcl-2、FN的蛋白表达。
5) renal fibrosis
肾间质纤维化
1.
Renal fibrosis may lead to the loss of renal function.
肾间质纤维化可导致肾功能损害 ,其发病机理主要与细胞外基质 (ECM )过度沉积及细胞因子、生长因子作用有关 ;其治疗方法主要是抑制纤维细胞活性及ECM合成 ,刺激ECM降解。
2.
Whereas Celecoxib markedly suppressed the expression of above-mentioned and im-proved renal fibrosis.
结果塞来昔布及吲哚美辛均可以降低尿TXB2浓度,以塞来昔布组更为显著;与对照组相比,其余3组MCP-1、TGF-β1及ColⅣ的蛋白表达水平均显著上升,肾间质纤维化严重;塞来昔布治疗后,上述蛋白表达水平显著下调,肾间质纤维化程度明显减轻。
6) interstitial fibrosis
肾间质纤维化
1.
Effect of estrogen on tubular epithelial cell epithelial phenotype transdifferention in experimental interstitial fibrosis rats;
雌激素对实验性肾间质纤维化大鼠肾小管上皮细胞表型转化的影响
2.
AIM: To observe the roles of rosiglitazone (RSG) in unilateral ureteral obstruction (UUO) rats renal interstitial fibrosis.
目的 :探讨罗格列酮 (RSG)对单侧输尿管梗阻 (UUO)大鼠肾间质纤维化的保护作用及其机制。
3.
Methods The changes of podocytes with their area, number and the relationship of these changes with SCC and interstitial fibrosis were studied in twenty-two cases of human DIA.
结论在DIA病人 ,肾小球系膜面积的增加与肾间质纤维化的严重程度成正比 ;足细胞相对面积及相对数量的减少与血清肌酐浓度的升高及肾间质纤维化的严重程度成正比。
补充资料：弥漫性肺间质纤维化
弥漫性肺间质纤维化
，多种病因引起的以肺泡结构内的细胞及结缔组织基质发生紊乱，早期均表现为肺泡炎晚期为肺间质纤维化的一组异型的疾病。病变主要发生于肺间质、肺泡上皮、肺毛细血管内皮细胞和肺动、静脉。病种约有130个之多。其分类尚未统一，近年来倾向于将本病分为病因已明和病因未明二类，病因已明的如吸入各种粉尘、反复感染(病毒、细菌、真菌等），吸入气体(二氧化硫、氯、氧气等），所致的弥漫性间质性肺纤维化，原因未明的如隐原性致纤维性肺泡炎、肺纤维化伴发胶原-血管性疾病，肺出血-肾炎综合征等。由于肺间质纤维组织大量增生及肺泡弹性减弱，导致肺容量减少，限制性通气障碍、低氧血症等。临床症状以进行性气短、发绀及呼吸困难为主。X线检查可见弥漫网点状阴影及粗索条状阴影等。本病无特殊治疗，预后不佳。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条