Based on a new concept of protease-resistant long acting peptides design,the functional groups with proton-donors and proton-acceptors were introduced to the N-terminal and position 6 of LHRH antagonist,and a series of novel LHRH antagonist analogues were synthesized.

Improved synthesis of CCR5 antagonist TAK-779;

Advances in vascular endothelial growth factor antagonist therapy for ocular neovascularization diseases;

Role of angiotensin Ⅱand its receptor antagonists in endothelial cell apoptosis;

Progress in agonists and antagonists of peroxisome proliferator-activated receptor γ;