Regulation of macrophage cholesterol efflux and liver X receptor α activation by nicotine;

Effects of liver X receptor agonist on the expressions of C-reactive protein and CD40 ligand and contents of smooth muscle cells in the aorta of ApoE gene knockout mice

Activation of Liver X Receptors (LXRs) Upregulates Fatty Acid Synthase (FAS) Expression in Liver;

METHODS:To activate LXR and increase bile acid synthesis,C57BL/6J mice were fed T0901317 for 7 d and Wistar rats were fed a high-cholesterol diet for 2 wk.

Objective To understand the effect and mechanism of endothelin-1 (ET-1) regulated by liver X receptor (LXR) in vascular endothelial cell line EA.

Peroxisome proliferatoractivated receptors(PPARs)pathway, Liver X receptors(LXR)pathway and Sterol regulatory element binding proteins (SREBPs) pathway are involved in lipid metabolism.

Background Liver X receptors (LXRs) are members of the nuclear hormone receptor superfamily which involve in energy metabolism of intracellular cholesterol and glucose regulation.

The liver X receptors(LXRs) are the members of the NRs superfamily.

Purpose To build a three dimensional structure activity relationship model of the title compounds and gain further insights into requirements for potential nonsteroidal progesterone receptor agonists.

Significance and effect of liver X receptor α and sterol regulatory element binding protein-1c in non-alcoholic fatty liver disease in rats;

Besides, RT-PCR was applied to detect expression of liver X receptor α (LXRα) and ATP binding cassette transporter A1 (ABCA1) mRNA.

Aim To investigate the mechanism of ezetimibe-induced cholesterol efflux by observing the effect of ezetimibe on ATP binding cassettet transporter A1 and Liver X Receptor α in lipid-loaded cells derived from vascular smooth muscle cell(VSMC).