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1)  5-HT4 receptor partial agonist
5-HT4受体激动剂
2)  5-HT4 antagonist
5-HT4受体拮抗剂
3)  5-HT4 receptor
5-HT4受体
1.
Objective To investigate the effect of 5-hydroxytryptamine(5-HT) and the plasticity of 5-HT3 and 5-HT4 receptors in the myenteric plexus on the pathogenesis of irritable bowel syndrome(IBS) subgroups.
目的探讨5羟色胺(5-HT)以及5-HT3、5-HT4受体可塑性在肠易激综合征(IBS)不同亚型发病中的作用。
2.
In addition,the stimulation of 5-HT4 receptors elicits gastrointestinal contractile activity and increases the rate of gastric emptying in humans and dogs.
而刺激5-HT4受体会引起人和犬的胃肠收缩动作并提高胃排空率。
3.
Aim To investigate the pharmacological effects of 5-HT4 receptor agonist SHR116958 on its prokinetic activity with in vivo and in vitro animal models.
目的通过3种小鼠整体和离体豚鼠回肠模型,研究新5-HT4受体激动剂SHR116958促进胃肠蠕动的作用。
4)  serotonin 5-HT4 receptor isoforms
5-HT4受体亚型
1.
Objective:To investigate the mRNA expression of four serotonin 5-HT4 receptor isoforms(5-HT4Ra,5-HT4Rb,5-HT4Rg, 5-HT4Ri) in interatrial septum with atrial fibrillation(AF) and study its clinic significance.
术中取房间隔组织,采用SYBRGreen实时荧光定量PCR检测各组中5-HT4受体亚型mRNA的表达。
5)  5-HT_(1B/1D) receptor agonist
5-HT1B/1D受体激动剂
1.
AIM To synthesis a new type 5-HT_(1B/1D) receptor agonist.
目的合成一种新型的5-HT1B/1D受体激动剂。
6)  5-hydroxytryptamine receptor agonist
5-羟色胺受体激动剂
补充资料:受体激动剂


受体激动剂
receptor activating age?nts

  能与受体结合,且可使受体激动,从而表现出相应的生理效应或药理作用的药物。例如乙酰胆碱,可与M胆碱受体结合,并使之激动,产生腺体分泌增加,心率减慢、血管扩张、支气管及胃肠道平滑肌收缩和瞳孔缩小等效应。
  
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