3) mammalian target of rapamycin
哺乳动物雷帕霉素靶蛋白
1.
Mammalian target of rapamycin (mTOR) is a key downstream molecule of PI3K/Akt pathway.
哺乳动物雷帕霉素靶蛋白(mammalian target of rapamycin,mTOR)是PI3K/Akt通路的下游分子,可接受生长因子、营养、能量等多种信号,是细胞生长和增殖的关键调节分子。
2.
Objective:To investigate the effect of the mammalian target of rapamycin(mTOR)inhibitor CCI-779 on the chemosensitivity of androgen-independent prostate cancer cell line PC-3.
目的:研究哺乳动物雷帕霉素靶蛋白(mTOR)抑制剂CCI-779对激素非依赖型前列腺癌PC-3细胞株化疗敏感性的影响。
3.
Structure and function of mammalian target of rapamycin;
哺乳动物雷帕霉素靶蛋白(mTOR)参与细胞内一系列生理病理过程,其存在形式主要有两种:mTOR-Raptor复合物和mTOR-R ictor复合物。
4) mTOR
哺乳动物雷帕霉素靶蛋白
1.
To explore the expression rule of mammalian target of rapamycin (mTOR) gene in endometria of early pregnant mouse, real-time fluorescence quantitative PCR (RT FQ-PCR), in situ hybridization, immunohistochemistry and Western blotting were used to detect the mTOR mRNA and protein in the mouse endometria from unpregnant, pseudopregnant and pregnant d3, d4, d5, d6 and d7.
利用实时荧光定量PCR、原位杂交法、免疫组化(SP法)和Western印迹法分别检测未孕、假孕及孕d3、d4、d5、d6、d7小鼠子宫内膜哺乳动物雷帕霉素靶蛋白(mammaliantargetofrapamycin,mTOR)mRNA和蛋白质的表达,研究mTOR基因在早孕小鼠子宫内膜的表达规律。
2.
Objective To explore inhibitory effect of RNA interference with eukaryotic expression plasmid containing shRNA on expression of mTOR gene in human colon cell line LoVo.
目的探讨shRNA真核表达质粒介导的RNA干扰技术对人结肠癌LoVo细胞哺乳动物雷帕霉素靶蛋白(mTOR)基因表达的抑制作用。
3.
The proliferation of the cells was detected by MTT assay;the apoptosis rate and cell cycle were determined by flow cytometry(FCM);apoptosis of cells was observed by inverted microscopy;the cylin D1,CXCR4 and mTOR mRNA expressions were detected by RT-PCR or FQ-PCR after treating RPMI8226 cells with different concentrations of rapamycin.
不同浓度雷帕霉素作用于RPMI8226细胞不同时间,应用MTT检测细胞的增殖,流式细胞术检测细胞凋亡及细胞周期,半定量PCR检测雷帕霉素干预RPMI8226后细胞周期蛋白D1(cyclinD1)、CXCR4mRNA表达,荧光定量PCR检测哺乳动物雷帕霉素靶蛋白(mTOR)mRNA表达的影响。
5) mTOR
哺乳动物雷帕霉素靶体蛋白
6) mammalian target of Rapamycin(mTOR)
哺乳动物雷帕霉素靶蛋白(mTOR)
1.
Those mammalian target of rapamycin(mTOR)inhibitors such as sirolimus have both immunosuppressive effects on the grafts and targeted anti-tumor effects on the malignancies.
以西罗莫司为代表的哺乳动物雷帕霉素靶蛋白(mTOR)抑制剂除了具有强有力的免疫抑制作用外,其对恶性肿瘤的靶向治疗作用近年逐步得到确认,并在临床得到推广。
补充资料：哺乳动物细胞
分子式：
CAS号：
性质：来自哺乳动物体的细胞。它的培养由于可用来大量生产疫苗、重组蛋白和其他医疗产品而倍受重视。目前已建成许多重要的细胞系，这些细胞来自鼠、人、猴等。
CAS号：
性质：来自哺乳动物体的细胞。它的培养由于可用来大量生产疫苗、重组蛋白和其他医疗产品而倍受重视。目前已建成许多重要的细胞系，这些细胞来自鼠、人、猴等。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条