1) M3 receptor agonist
M3受体激动剂
1.
Aim To observe the protective effects of choline and pilocarpine,the M3 receptor agonists,on the arrhythmias of Wistar rats induced by barium chloride.
目的观察M3受体激动剂胆碱和毛果芸香碱对氯化钡诱发Wistar大鼠心律失常的保护作用。
2) M3-receptor antagonist
M3受体阻滞剂
1.
Darifenacin is a selective muscarinic M3-receptor antagonist that has been used in patients with overactive bladder syndrome (OAB).
达非那新是一种选择性M3受体阻滞剂,临床主要用于治疗膀胱过度活动综合征。
3) receptor agonists
受体激动剂
1.
Purpose To build a three dimensional structure activity relationship model of the title compounds and gain further insights into requirements for potential nonsteroidal progesterone receptor agonists.
目的 建立非甾体类孕酮受体激动剂5-亚苄基-1,2-二氢-5H-苯并吡喃并[3,4-f]喹啉衍生物的三维 定量构效模型,为设计高效的非甾体类孕酮受体激动剂提供理论依据。
4) M3 receptor
M3受体
1.
OBJECTIVE To investigate the protective effects of M3 receptor agonist pilocarpine on myocardial ischemia-reperfusion injury in isolated rat hearts.
目的研究M3受体激动剂毛果芸香碱对离体大鼠心肌缺血再灌注损伤的保护作用。
2.
M3 receptor is one of muscarinic receptor subtypes which were classified by the difference of gene expression and pharmacology.
根据M受体的基因表达和药理作用的不同可以分成五种亚型,分别是M1-M5,M3受体是其中的一种。
3.
Objective To observe the effect of activation of M3 receptor on H2O2 induced apoptosis in cultured rat myocytes and to investigate its possible mechanisms.
目的探讨M3受体激动对H2O2诱导的大鼠培养心肌细胞凋亡的作用及其机制。
5) M_3 receptor
M3受体
1.
Methods Using the acute ischemic model of rats and patch-clamp techniques, the effects of the M_3 receptor on the occurrence of arrhythmias and its possible mechanisms were studied.
目的 研究心脏M3受体 /M3受体介导的钾通道与心律失常的关系,寻找抗心律失常药物的新靶点。
2.
To detect the function and expression of ventricular M_3 receptor(M_3R)in cerebral-cardiac syndrome(CCS)model rats and to explore the relationship between the expression of M_3R and the arrhythmia resulted from CCS,CCS model rats were induced by occluding right middle cerebral artery.
观察M3受体(M3R)在脑心综合征(CCS)模型大鼠心室肌中的作用及其表达,以探讨其与CCS心律失常的关系。
3.
Protective effect of M_3 receptor on H_2O_2-induced apoptosis of rat myocardial cells in vitro;
目的 探讨M3受体激动对H2 O2 诱导的大鼠培养心肌细胞凋亡的作用 ,进一步阐明其机制。
6) M 3 receptor
M3受体
1.
Objective To observe the effects of M 3 receptor on myocytes injury of rats.
目的 探讨激动M3受体对心肌细胞损伤的保护作用。
补充资料：受体激动剂
受体激动剂
receptor activating age?nts
能与受体结合，且可使受体激动，从而表现出相应的生理效应或药理作用的药物。例如乙酰胆碱，可与M胆碱受体结合，并使之激动，产生腺体分泌增加，心率减慢、血管扩张、支气管及胃肠道平滑肌收缩和瞳孔缩小等效应。
说明：补充资料仅用于学习参考，请勿用于其它任何用途。
参考词条