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1)  laminin α5
层粘连蛋白α_5
1.
Objective: To obtain the laminin α5 LG3 recombinant protein with 6×His tag by prokaryotic expression.
目的:用原核表达的方法获得带有6×His标记的小鼠层粘连蛋白α_5 LG3组件的重组蛋白。
2)  Laminin ['læminin]
层粘连蛋白
1.
Clinical significance of serum laminin in patients with epithelial ovarian tumor;
卵巢上皮性肿瘤患者血清层粘连蛋白检测的临床意义
2.
Relationship between tumor necrosis factor as well as laminin and Hepatic Diseases;
肿瘤坏死因子及层粘连蛋白与肝病的关系
3.
Clinical significance of urinary lamininin patients with colorectal cancer;
大肠癌患者尿液层粘连蛋白检测及临床意义
3)  Fibronectin
层粘连蛋白
1.
To Study the Expression of Integrin β_3 and Extracellular Matrix of Fibronectin and Laminin in Tubal Pregnancy;
输卵管妊娠中整合素β_3及细胞基质成分层粘连蛋白及纤粘连蛋白表达的研究
2.
Methods:Developed a mouse model of liver cirrhosis and liver m etastases from colorectal cancer,observed the incidence of liver metastasis in cirrhosis liver mice and normal liver mice;examined the expression of liminin( LN),fibronectin(FN) and E-selectin in livers by immunohistochemistry(IH).
方法:诱导小鼠肝硬化及结肠癌肝转移模型,比较正常肝与肝硬化小鼠肝转移率;免疫组化法测定层粘连蛋白(laminin,LN)、纤维连接蛋白(fibronectin,FN)及E-选择素(E-selectin)在小鼠肝脏的表达。
3.
To investigate the expression of fibronectin(FN) and laminin(LN) in prolonged uterine bleeding after mifepristone induced abortion, 20 specimens from curettage were obtained from 20 women who had prolonged uterine bleeding after termination of early pregnancy by mifepristone and misoprostol.
为探讨层粘连蛋白 (LM)及纤维粘连蛋白 (FN)在米非司酮药物流产 (以下简称药流 )后子宫持续出血时的表达 ,对 2 0例米非司酮 +米索前列醇药物流产后子宫出血 (出血组 )的刮出组织及 1 0例人工流产负压吸宫术吸出的组织 (对照组 ) ,用HE及免疫组织化学方法染色并观察标本。
4)  LN
层粘连蛋白
1.
Consecutive Changes of HA, LN in BALF and Vein in Blemycine-induced Pulmonary Fibrosis in Rats;
博莱霉素致肺纤维化大鼠血和支气管肺泡灌洗液中透明质酸和层粘连蛋白含量的动态变化
2.
RELATION BETWEEN SERUM LEVEL OF HYALURONIC ACID, PROCOLLAGEN Ⅲ,COLLAGEN Ⅳ,LN AND LIVER FIBROSIS;
血清透明质酸、Ⅲ型前胶原、IV型胶原、层粘连蛋白水平与肝纤维化的关系
3.
Effect of LN and CMECs on Differentiation of NSCs
层粘连蛋白与脑微血管内皮细胞对神经干细胞分化的影响
5)  laminin receptor
层粘连蛋白受体
1.
Analysis on gene expression profile of laminin receptor;
层粘连蛋白受体基因表达谱分析
2.
Expression of 67kD laminin receptor in three ovarian carcinoma cells;
67kD层粘连蛋白受体在三种卵巢癌细胞株中表达的研究
3.
Expression of 67 kDa laminin receptor in gallbladder carcinomas and its significance;
67kDa层粘连蛋白受体在胆囊癌中的表达及意义
6)  laminin 5(LN5)
层粘连蛋白5
1.
Objective To investigate the relationships of the expression levels of laminin 5(LN5) and epidermal growth factor receptor (EGFR) in the tumor tissues of lung cancer patients,and provide clues for the individual target therapy of EGFR tyrosine kinase inhibitor (EGFR-TKI).
目的探讨肺癌患者肿瘤组织中层粘连蛋白5(LN5)和表皮生长因子受体(EGFR)表达水平的关系,为EGFR酪氨酸激酶抑制剂(EGFR-TKI)个体化靶向治疗提供依据。
补充资料:层粘连蛋白
分子式:
CAS号:

性质:又称膜层蛋白。由基底膜的上皮细胞、内皮细胞以及一些肿瘤细胞株(如畸胎瘤GP-2)产生的一种糖蛋白。分子量83000。由三条多肽链组成:A链40000,B1链22500和B2链20500。三条肽链短臂上球形结构可以和IV型胶原结合,短臂的非球型部具有和细胞结合的活性。通过LN中介,细胞可黏附在基底膜基质上。层粘连蛋白作为细胞基底膜基质的重要组成成分,参与体内的炎症反应、免疫效应、肿瘤转移等生理、病理过程。

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