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1)  Plasmodium falciparum CTL epitope vaccine
恶性疟CTL表位疫苗
2)  epitope vaccine
表位疫苗
1.
The protective immunity induced by the epitope vaccines from two new novel genes of Toxoplasma gondii in mice;
弓形虫新基因表位疫苗免疫效果的观察
2.
The single-epitope vaccines pcDNA3-W2b, pcDNA3-W2a and double-epitope vaccine pcDNA3-W2b2a were successfully constructed.
采用生物信息学方法对弓形虫新基因wx2进行表位分析预测,PCR扩增基因中编码2个表位的片段W2b和W2a,成功构建新基因的单表位疫苗质粒pcDNA3-W2b、pcDNA3-W2a和双表位疫苗pcDNA3-W2b2a,接种小鼠,观察表位疫苗的免疫保护作用。
3.
Objective Epitope vaccine is a special type of vaccine to combat the infection disease、cancer and autoimmune disease.
目的 表位疫苗是近年来发展起来的一种独特的疫苗设计思路,是目前研制感染性疾病、恶性肿瘤以及自身免疫性疾病等疫苗设计的新方向。
3)  epitope-specific CTL
表位特异性CTL
1.
Optimizing the conditions for in vitro expansion of HBV protein epitope-specific CTLs
乙肝病毒蛋白抗原表位特异性CTL体外扩增条件优化
4)  Malaria vaccine
疟疾疫苗
1.
Although the knowledge of the parasite s biological behaviors is indefinite, significant progress has been made in the development of malaria vaccine during the last 30 years.
尽管疟原虫的生物学研究仍不甚明晰 ,疟疾疫苗的研究在最近的 30年中仍取得了明显的成果。
2.
The major Merozoite Surface Protein 1(MSP1) of Plasmodium falciparum is an important candidate for malaria vaccine.
恶性疟原虫裂殖子表面蛋白 1是当今疟疾疫苗主要的候选抗原。
3.
While an effective malaria vaccine is not yet available, considerable insight has been gained in the complex, mu.
因此,研制高效疟疾疫苗是控制和消灭疟疾的重要途径。
5)  CTL epitope
CTL表位
1.
Applying three dimensional amino acid index of nonbonding interaction to quantitative prediction of HLA-A*0201-restricted CTL epitope;
氨基酸非键作用指数用于HLA-A*0201限制性CTL表位定量预测研究
2.
Study on low affinity CTL epitopes in the development of therapeutic tumor vaccine;
低亲和力CTL表位肽在治疗性肿瘤疫苗中应用的研究
3.
Prediction of H-2Kb restricted CTL epitope of heparanase and affinity assay of these epitopes with MHC-I molecule;
小鼠肝素酶H-2K~b限制性CTL表位预测及其MHC-I亲和力分析
6)  CTL epitopes
CTL表位
1.
Prediction of CTL epitopes based on modified artificial neural network;
基于改进的人工神经网络方法预测CTL表位
2.
Objective To predict the HLA-A2/A3-restricted CTL epitopes of COX-2 and MAGE-4 hyper-expressed in esophageal carcinoma(ECC).
目的预测食管癌普遍高表达蛋白COX-2和MAGE-4的HLA-A2/A3限制性CTL表位。
3.
Objective To study the model of the quantitative structure-activity relationship (QSAR) CTL epitopes binding to MHC molecule.
目的研究了CTL表位与MHC分子结合的定量构效关系模型。
补充资料:恶性疟


恶性疟
malignant malaria

疟原虫引起的传染病,有引起疟疾病凶险发作的可能,传播媒介是雌性按蚊。临床症状复杂而多样化。发热前寒战较少,可仅有畏寒,头痛、肌痛、恶心、呕吐、烦渴等症状较显著。热型多不规则。贫血和脾肿大显著,重症有黄疸和肝功能损害,并易致凶险发作。一般治疗同其他传染病。控制临床发作,可选用消灭病原体的药物如氯喹、奎宁、磷酸咯啶、磷酸咯萘啶、甲氧苄胺嘧啶等。
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